Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11965505 | 0.84 | HTT (0.53) | KDM4EALDH1A1HPGDPKMHTT | |
| SCHEMBL10736543 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1HPGDPKMHTT | |
| SCHEMBL17225269 | 0.81 | KDM4E (0.55) | KDM4EALDH1A1HPGDPKMHTT | |
| SCHEMBL15398916 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1HPGDPKMHTT | |
| SCHEMBL9902684 | 0.81 | KDM4E (0.55) | KDM4EALDH1A1HPGDPKMHTT | |
| SCHEMBL9923049 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1HPGDPKMHTT | |
| SCHEMBL10553462 | 0.76 | KDM4E (0.59) | KDM4EALDH1A1HPGDPKMHTT | |
| SCHEMBL16543489 | 0.74 | KDM4E (0.50) | KDM4EALDH1A1HPGDPKMHTT | |
| SCHEMBL443469 | 0.73 | HTT (0.72) | KDM4EALDH1A1HPGDPKMHTT | |
| SCHEMBL9923048 | 0.72 | KDM4E (0.51) | KDM4EALDH1A1HPGDPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9175031-B2 | Ketolide compounds | WOCKHARDT LIMITED (IN) | 2015-11-03 | — | — | US | disclosed |