Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16543489 | 0.87 | KDM4E (0.50) | KDM4EALDH1A1HPGDPKMNPC1 | |
| SCHEMBL10553462 | 0.78 | KDM4E (0.59) | KDM4EALDH1A1HPGDPKMNPC1 | |
| SCHEMBL14369743 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1HPGDPKMNPC1 | |
| SCHEMBL29816697 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1HPGDPKMNPC1 | |
| SCHEMBL20025653 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1HPGDPKMNPC1 | |
| SCHEMBL11982529 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1HPGDPKMNPC1 | |
| SCHEMBL18027865 | 0.74 | FAAH (0.46) | KDM4EALDH1A1HPGDPKMCYP1A2 | |
| SCHEMBL17659943 | 0.73 | NPC1 (0.55) | KDM4EALDH1A1HPGDPKMNPC1 | |
| SCHEMBL17225320 | 0.72 | KDM4E (0.46) | KDM4EALDH1A1HPGDPKMNPC1 | |
| SCHEMBL9923047 | 0.71 | KDM4E (0.62) | KDM4EALDH1A1HPGDPKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076989-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2012-06-14 | — | — | WO | disclosed |