Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | CFD | P00746 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204151 | 0.75 | RECQL (0.48) | RECQLHSD11B1 | |
| SCHEMBL26348654 | 0.74 | RECQL (0.32) | RECQLPHGDH | |
| SCHEMBL14899511 | 0.74 | — | — | |
| SCHEMBL649369 | 0.72 | CHRM2 (0.46) | RECQLHSD11B1 | |
| SCHEMBL21442076 | 0.72 | CHRM2 (0.46) | RECQLHSD11B1 | |
| SCHEMBL6205600 | 0.71 | ALDH1A1 (0.42) | RECQLPHGDHHSD11B1 | |
| SCHEMBL647647 | 0.71 | ALDH1A1 (0.42) | RECQLPHGDHHSD11B1 | |
| SCHEMBL648430 | 0.71 | — | — | |
| SCHEMBL28209715 | 0.71 | EPHX1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL28210173 | 0.69 | EPHX1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272825-B1 | Protected amino hydroxy adamantane carboxylic acid and process for its preparation | ASTRAZENECA AB (SE) | 2015-11-04 | — | — | EP | disclosed |