Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15079741 | 0.83 | LMNA (0.67) | HTTLMNATP53CYP3A4HTR2A | |
| SCHEMBL8207699 | 0.83 | LMNA (0.67) | HTTLMNATP53CYP3A4HTR2A | |
| SCHEMBL23123473 | 0.83 | LMNA (0.67) | HTTLMNATP53CYP3A4HTR2A | |
| SCHEMBL29757882 | 0.83 | LMNA (0.67) | HTTLMNATP53CYP3A4HTR2A | |
| SCHEMBL1911434 | 0.82 | LMNA (0.48) | HTTLMNATP53CYP3A4HTR2A | |
| Hydrochloric Acid SCHEMBL14120711 | 0.81 | LMNA (0.64) | HTTLMNATP53CYP3A4HTR2A | |
| SCHEMBL7435118 | 0.80 | TP53 (0.63) | HTTLMNATP53CYP3A4TSHR | |
| Hydrogen Peroxide SCHEMBL29099641 | 0.78 | HTR2B (0.51) | HTTLMNATP53CYP3A4HTR2A | |
| SCHEMBL21095998 | 0.78 | HTT (0.45) | HTTLMNATP53CYP3A4HTR2A | |
| SCHEMBL17226365 | 0.78 | LMNA (0.37) | HTTLMNATP53CYP3A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403860-B1 | PHOSPHOTHIOPHENE AND PHOSPHOTHIAZOLE AS HCV POLYMERASE INHIBITORS | IDENIX PHARMACEUTICALS INC (US) | 2015-11-04 | — | — | EP | disclosed |