Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | HPGD | P15428 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 9/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29392124 | 0.89 | NPC1 (0.55) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL39752 | 0.89 | NPC1 (0.55) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL10236278 | 0.82 | F2RL3 (0.45) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL10279218 | 0.82 | NPC1 (0.49) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL5313990 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL13183738 | 0.80 | HSD17B10 (0.59) | ALDH1A1HPGDKDM4EMAPTTDP1 | |
| SCHEMBL29531707 | 0.79 | NPC1 (0.69) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL824375 | 0.79 | NPC1 (0.69) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL2590623 | 0.78 | GPR119 (0.52) | ALDH1A1HPGDKDM4EMAPTTDP1 | |
| SCHEMBL12564963 | 0.76 | RPS6KB2 (0.51) | ALDH1A1HPGDKDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403860-B1 | PHOSPHOTHIOPHENE AND PHOSPHOTHIAZOLE AS HCV POLYMERASE INHIBITORS | IDENIX PHARMACEUTICALS INC (US) | 2015-11-04 | — | — | EP | disclosed |