Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 6/20 | 0.43 |
| ▸ | DRD3 | P35462 | 6/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3845038 | 0.90 | DRD2 (0.47) | VCPDRD2DRD3SLC6A2SLC6A4 | |
| SCHEMBL14346806 | 0.85 | NOTUM (0.45) | VCPDRD2DRD3SLC6A2SLC6A4 | |
| SCHEMBL3853616 | 0.82 | DRD2 (0.48) | VCPDRD2DRD3SLC6A2SLC6A4 | |
| SCHEMBL4496072 | 0.79 | GPR119 (0.54) | VCPDRD2DRD3 | |
| SCHEMBL3853660 | 0.78 | DRD2 (0.50) | DRD2DRD3SLC6A2SLC6A4 | |
| SCHEMBL3853868 | 0.78 | DRD2 (0.50) | DRD2DRD3SLC6A2SLC6A4 | |
| SCHEMBL3845208 | 0.76 | DRD2 (0.48) | DRD2DRD3SLC6A2SLC6A4SIGMAR1 | |
| SCHEMBL3843937 | 0.76 | DRD2 (0.53) | DRD2DRD3SLC6A2SLC6A4SIGMAR1 | |
| SCHEMBL14346795 | 0.76 | GFER (0.47) | DRD2DRD3SLC6A2SLC6A4 | |
| SCHEMBL3847168 | 0.76 | DRD2 (0.47) | DRD2DRD3SLC6A2SLC6A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038268-B1 | CARBONYLATED (AZA)CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET SOC CIV (FR) | 2015-11-04 | — | — | EP | disclosed |