Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 11/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13767017 | 0.90 | CPB2 (0.41) | CPB2THRBMEN1HTTKMT2A | |
| SCHEMBL13767026 | 0.90 | CPB2 (0.41) | CPB2THRBMEN1HTTKMT2A | |
| SCHEMBL13767025 | 0.86 | CPB2 (0.42) | CPB2THRBMEN1HTTKMT2A | |
| SCHEMBL13767024 | 0.86 | CPB2 (0.42) | CPB2THRBMEN1HTTKMT2A | |
| SCHEMBL13767023 | 0.86 | CPB2 (0.42) | CPB2THRBMEN1HTTKMT2A | |
| SCHEMBL13767015 | 0.81 | HSD11B1 (0.40) | HTTCNR2CNR1 | |
| SCHEMBL13767016 | 0.81 | PLAT (0.36) | — | |
| SCHEMBL13772137 | 0.76 | JAK2 (0.34) | SMN1; SMN2CNR2CNR1 | |
| SCHEMBL13766992 | 0.72 | HSD11B1 (0.39) | HTTCNR2CNR1 | |
| SCHEMBL13766746 | 0.72 | HSD11B1 (0.40) | HTTCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953145-B1 | HETEROCYCLIC COMPOUND HAVING INHIBITORY ACTIVITY ON 11-B-HYDROXYSTEROID DEHYDROGENASE TYPE I | SHIONOGI & CO (JP) | 2015-11-04 | — | — | EP | disclosed |