Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3930953 | 0.94 | LMNA (0.46) | LMNAKMT2APOLBCYP2D6ALDH1A1 | |
| SCHEMBL3930947 | 0.94 | LMNA (0.46) | LMNAKMT2APOLBCYP2D6ALDH1A1 | |
| SCHEMBL3938254 | 0.88 | LMNA (0.48) | LMNAKMT2APOLBCYP2D6ALDH1A1 | |
| SCHEMBL3938256 | 0.88 | LMNA (0.48) | LMNAKMT2APOLBCYP2D6ALDH1A1 | |
| SCHEMBL15501143 | 0.81 | ANPEP (0.38) | KMT2APOLBMAPTKDM4E | |
| SCHEMBL2003089 | 0.81 | ANPEP (0.38) | KMT2APOLBMAPTKDM4E | |
| SCHEMBL2003090 | 0.81 | ANPEP (0.38) | KMT2APOLBMAPTKDM4E | |
| SCHEMBL28474870 | 0.81 | LMNA (0.58) | LMNAKMT2APOLBCYP2D6ALDH1A1 | |
| SCHEMBL28474871 | 0.81 | LMNA (0.58) | LMNAKMT2APOLBCYP2D6ALDH1A1 | |
| SCHEMBL29961368 | 0.81 | LMNA (0.58) | LMNAKMT2APOLBCYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940028-A1 | CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE | CORIXA CORPORATION (US) | 2015-11-04 | — | — | EP | disclosed |