Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | KYNU | Q16719 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28474871 | 1.00 | LMNA (0.58) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL29961368 | 1.00 | LMNA (0.58) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL2007087 | 0.86 | LMNA (0.76) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL2007088 | 0.86 | LMNA (0.76) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL12837317 | 0.86 | LMNA (0.76) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL19903806 | 0.84 | LMNA (0.59) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL2006966 | 0.83 | LMNA (0.60) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL2006970 | 0.83 | LMNA (0.60) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL20857679 | 0.82 | CYP2D6 (0.54) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL17227495 | 0.81 | LMNA (0.51) | LMNAKMT2APOLBALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111867623-B | TOLL-like receptor ligands | 英尼穆内公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-111867623-A | TOLL-like receptor ligands | 英尼穆内公司 | 2020-10-30 | — | — | CN | disclosed |