Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 5/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2258833 | 0.85 | THRA (0.39) | THRATHRBESR1ESR2KMT2A | |
| SCHEMBL994871 | 0.82 | THRA (0.42) | THRATHRBESR1ESR2KMT2A | |
| SCHEMBL11804504 | 0.80 | HPGD (0.46) | ESR1ESR2KMT2AHPGDALDH1A1 | |
| SCHEMBL20707173 | 0.77 | THRA (0.44) | THRATHRBESR1ESR2KMT2A | |
| SCHEMBL309176 | 0.75 | THRA (0.44) | THRATHRBESR1ESR2KMT2A | |
| SCHEMBL14446922 | 0.75 | KDM4E (0.46) | ESR1ESR2KMT2AHPGDCYP3A4 | |
| SCHEMBL27666403 | 0.75 | SLC6A4 (0.55) | ESR1ESR2KMT2AALDH1A1TSHR | |
| SCHEMBL515470 | 0.74 | SLC6A2 (0.52) | ALDH1A1CYP3A4 | |
| SCHEMBL1362104 | 0.73 | ALDH1A1 (0.54) | THRATHRBKMT2AALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL11513172 | 0.71 | SLC6A2 (0.48) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2082875-B1 | Lithographic printing plate precursor and plate making method using the precursor | FUJIFILM CORP (JP) | 2012-03-07 | — | — | EP | disclosed |