SCHEMBL17228705

SCHEMBL17228705

c1ccc(-c2ccc(-c3ccc4oc5c(-n6c7ccccc7c7ccccc76)cc(-c6ccccc6)cc5c4c3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.42
PLA2G4A P47712 4/20 0.42
PRKDC P78527 4/20 0.40
KDM4E B2RXH2 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 1/20 0.39
PLA2G10 O15496 1/20 0.37
PGR P06401 1/20 0.37
PIM1 P11309 1/20 0.35
CSNK2A2 P19784 1/20 0.35
CSNK2B P67870 1/20 0.35
PIM3 Q86V86 1/20 0.35
PIM2 Q9P1W9 1/20 0.35
ALDH1A1 P00352 2/20 0.35
TSPO P30536 1/20 0.34
GAA P10253 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 1/20 0.33
PTPN1 P18031 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14867871 0.93 PLA2G2A (0.37) PLA2G2APLA2G4APRKDCKDM4EL3MBTL1
SCHEMBL22113032 0.92 KDM4E (0.41) PLA2G2APLA2G4APRKDCKDM4EL3MBTL1
SCHEMBL9890300 0.92 KDM4E (0.41) PLA2G2APLA2G4APRKDCKDM4EL3MBTL1
SCHEMBL24739518 0.92 KDM4E (0.41) PLA2G2APLA2G4APRKDCKDM4EL3MBTL1
SCHEMBL17166618 0.91 PRKDC (0.40) PLA2G2APLA2G4APRKDCKDM4EL3MBTL1
SCHEMBL5028174 0.91 PLA2G2A (0.36) PLA2G2APLA2G4APRKDCKDM4EL3MBTL1
SCHEMBL17166658 0.90 PLA2G2A (0.39) PLA2G2APLA2G4APRKDCKDM4EL3MBTL1
SCHEMBL5028457 0.89 L3MBTL1 (0.42) PLA2G2APLA2G4APRKDCKDM4EL3MBTL1
SCHEMBL17166687 0.89 PRKDC (0.38) PLA2G2APLA2G4APRKDCKDM4EL3MBTL1
SCHEMBL5029864 0.89 PLA2G2A (0.36) PLA2G2APLA2G4APRKDCKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10774261-B2 Organic electroluminescence element, illumination device, and display device Konica Minolta, Inc. (JP) 2020-09-15 US disclosed
US-20150318489-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, ILLUMINATION DEVICE, AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-11-05 US disclosed
US-20150318489-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, ILLUMINATION DEVICE, AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-11-05 US disclosed