SCHEMBL17228758

SCHEMBL17228758

c1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cccc3c2sc2c(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cccc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ATM Q13315 1/20 0.43
ALOX5 P09917 1/20 0.37
TSPO P30536 3/20 0.35
ALDH1A1 P00352 2/20 0.33
LIMK1 P53667 1/20 0.33
HDAC4 P56524 1/20 0.33
KMT2A Q03164 2/20 0.33
IL1R1 P14778 1/20 0.33
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
PTGER4 P35408 1/20 0.32
PRKDC P78527 1/20 0.31
DNM1 Q05193 1/20 0.31
KDR P35968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17640315 0.96 L3MBTL1 (0.44) L3MBTL1KDM4EATMALOX5TSPO
SCHEMBL10331654 0.96 L3MBTL1 (0.44) L3MBTL1KDM4EATMALOX5TSPO
SCHEMBL24677556 0.95 KDM4E (0.40) L3MBTL1KDM4EATMALOX5TSPO
SCHEMBL10165747 0.93 L3MBTL1 (0.45) L3MBTL1KDM4EATMALOX5TSPO
SCHEMBL10165737 0.93 L3MBTL1 (0.47) L3MBTL1KDM4EATMALOX5TSPO
SCHEMBL17057179 0.92 ALOX5 (0.36) L3MBTL1KDM4EATMALOX5TSPO
SCHEMBL18020777 0.92 L3MBTL1 (0.44) L3MBTL1KDM4EATMALOX5TSPO
SCHEMBL18020786 0.92 L3MBTL1 (0.44) L3MBTL1KDM4EATMALOX5TSPO
SCHEMBL10165693 0.91 L3MBTL1 (0.49) L3MBTL1KDM4EATMALOX5TSPO
SCHEMBL21944784 0.91 L3MBTL1 (0.43) L3MBTL1KDM4EATMALOX5TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10774261-B2 Organic electroluminescence element, illumination device, and display device Konica Minolta, Inc. (JP) 2020-09-15 US disclosed
US-20150318489-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, ILLUMINATION DEVICE, AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-11-05 US disclosed
US-20150318489-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, ILLUMINATION DEVICE, AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-11-05 US disclosed