SCHEMBL172292

SCHEMBL172292

CCc1ccc(Oc2ccc(C(C)C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.48
L3MBTL1 Q9Y468 3/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
ATM Q13315 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
SMN1; SMN2 Q16637 4/20 0.42
NPBWR1 P48145 2/20 0.41
ACACB O00763 1/20 0.41
ACACA Q13085 1/20 0.41
KDM4E B2RXH2 1/20 0.41
POLB P06746 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MCHR1 Q99705 1/20 0.40
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19012462 0.88 NPC1 (0.42) IDO1L3MBTL1TSHRMAPK1ATM
SCHEMBL23381296 0.87 ALDH1A1 (0.46) IDO1L3MBTL1TSHRMAPK1ATM
SCHEMBL139408 0.87 L3MBTL1 (0.56) IDO1L3MBTL1TSHRMAPK1ATM
SCHEMBL10030394 0.87 MAPT (0.47) L3MBTL1TDP1RXRARXRBNPC1
SCHEMBL475215 0.84 SMN1; SMN2 (0.48) RXRARXRBNPC1RAB9ASMN1; SMN2
SCHEMBL15849015 0.84 ALDH1A1 (0.48) IDO1TSHRTDP1RAB9ASMN1; SMN2
SCHEMBL4366979 0.84 ALDH1A1 (0.48) IDO1TSHRTDP1RAB9ASMN1; SMN2
SCHEMBL8925998 0.84 SMN1; SMN2 (0.48) RXRARXRBNPC1RAB9ASMN1; SMN2
SCHEMBL25620748 0.84 TSHR (0.42) L3MBTL1TSHRMAPK1ATMTDP1
SCHEMBL25765970 0.84 TSHR (0.42) L3MBTL1TSHRMAPK1ATMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11746166-B2 UV active derivatives of pd(AcAc)2L catalyzed polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2023-09-05 US disclosed
WO-2023158767-A1 DUAL CATALYST SYSTEM FOR MASS VINYL ADDITION AND CATIONIC POLYMERIZABLE COMPOSITIONS PROMERUS, LLC (US) 2023-08-24 WO disclosed
WO-2023158768-A1 DUAL CATALYST SYSTEM FOR MASS ROMP AND CATIONIC POLYMERIZABLE COMPOSITIONS PROMERUS, LLC (US) 2023-08-24 WO disclosed
US-20230266668-A1 DUAL CATALYST SYSTEM FOR MASS ROMP AND CATIONIC POLYMERIZABLE COMPOSITIONS PROMERUS, LLC (US) 2023-08-24 US disclosed
US-20230220132-A1 FAST PHOTOCURABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL OR 3D PRINTING MATERIALS PROMERUS, LLC (US) 2023-07-13 US disclosed
US-11667731-B2 Stabilized UV active organopalladium compounds as vinyl addition catalysts PROMERUS, LLC (US) 2023-06-06 US disclosed
US-11639405-B2 Fast photocurable polycycloolefin compositions as optical or 3D printing materials PROMERUS, LLC (US) 2023-05-02 US disclosed
US-11155646-B2 Charge-bearing cyclodextrin polymeric materials and methods of making and using same CYCLOPURE, INC. (US) 2021-10-26 US disclosed
US-20210163631-A1 CHARGE-BEARING CYCLODEXTRIN POLYMERIC MATERIALS AND METHODS OF MAKING AND USING SAME AVENUE GLOBAL DISLOCATION OPPORTUNITIES FUND, L.P. AND AVENUE GLOBAL OPPORTUNITIES MASTER FUND, L.P. 2021-06-03 US disclosed
US-9622991-B2 Hematopoietic growth factor mimetic small molecule compounds and their uses LIGAND PHARMACEUTICALS INC. (US) 2017-04-18 US disclosed
EP-1255738-B1 GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO NEUROCRINE BIOSCIENCES INC (US) 2012-03-07 EP disclosed