Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.63 |
| ▸ | MPO | P05164 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7368184 | 0.88 | TAAR1 (0.67) | TAAR1MPOHPGDMEN1KMT2A | |
| SCHEMBL17033966 | 0.86 | TAAR1 (0.66) | TAAR1MPOHPGDMEN1KMT2A | |
| SCHEMBL21674321 | 0.82 | MPO (0.59) | TAAR1MPOHPGDMEN1KMT2A | |
| SCHEMBL172536 | 0.80 | TAAR1 (0.58) | TAAR1MPOHPGDMEN1KMT2A | |
| SCHEMBL172266 | 0.79 | TAAR1 (0.62) | TAAR1MPOHPGDMEN1KMT2A | |
| SCHEMBL30866618 | 0.79 | TAAR1 (0.62) | TAAR1MPOHPGDMEN1KMT2A | |
| SCHEMBL20615042 | 0.78 | CHRM2 (0.52) | TAAR1MPOMEN1KMT2ACHRM2 | |
| SCHEMBL25046557 | 0.78 | MPO (0.58) | TAAR1MPOHPGDMEN1KMT2A | |
| SCHEMBL22762068 | 0.78 | TAAR1 (0.59) | TAAR1MPOHPGDMEN1KMT2A | |
| SCHEMBL22762050 | 0.78 | TAAR1 (0.59) | TAAR1MPOHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247860-A1 | BROAD SPECTRUM ANTIVIRAL COMPOUNDS TARGETING THE SKI COMPLEX | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2020-12-10 | — | — | WO | disclosed |
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |