SCHEMBL172266

SCHEMBL172266

CCCc1ccccc1F

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TAAR1 Q96RJ0 4/20 0.62
▸ AOC3 Q16853 1/20 0.55
▸ IDO1 P14902 2/20 0.46
▸ MPO P05164 2/20 0.44
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ GFER P55789 1/20 0.42
▸ EPHX2 P34913 1/20 0.42
▸ LMNA P02545 1/20 0.42
▸ DAO P14920 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ MAOB P27338 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.41
▸ RIPK1 Q13546 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30866618 1.00 TAAR1 (0.62) TAAR1AOC3IDO1MPOMEN1
Ammonia Solution, Strong SCHEMBL6195354 0.98 TAAR1 (0.60) TAAR1AOC3IDO1MPOMEN1
Ethyne SCHEMBL27645780 0.95 TAAR1 (0.58) TAAR1AOC3IDO1MPOMEN1
SCHEMBL1073302 0.86 TAAR1 (0.58) TAAR1AOC3IDO1MPO
SCHEMBL14402410 0.84 TAAR1 (0.56) TAAR1AOC3MPOMEN1KMT2A
SCHEMBL8526001 0.84 TAAR1 (0.75) TAAR1AOC3IDO1MPOLMNA
SCHEMBL19540031 0.82 LIPG (0.58) TAAR1AOC3MPOMEN1KMT2A
SCHEMBL2241863 0.82 LIPG (0.58) TAAR1AOC3MPOMEN1KMT2A
SCHEMBL19540033 0.82 LIPG (0.58) TAAR1AOC3MPOMEN1KMT2A
SCHEMBL2584935 0.82 LIPG (0.58) TAAR1AOC3MPOMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1234460-C Regeneration process for solid acid catalyst CHINA PETROCHEMICAL CROP (CN) 2006-01-04 — — CN claimed
CN-1234459-C Application method of solid acid catalyst CHINA PETROCHEMICAL CORP (CN) 2006-01-04 — — CN claimed
CN-1541768-A Application method of solid acid catalyst 中国石油化工股份有限公司 2004-11-03 — — CN claimed
CN-1520928-A Regeneration process for solid acid catalyst 中国石油化工股份有限公司 2004-08-18 — — CN claimed
WO-2023240253-A2 MODULATORS OF TNF-ALPHA ACTIVITY FORWARD THERAPEUTICS, INC. (US) 2023-12-14 — — WO disclosed
WO-2023235548-A1 SQUARAMIDE DERIVATIVES AS CB1 ALLOSTERIC MODULATORS RESEARCH TRIANGLE INSTITUTE (US) 2023-12-07 — — WO disclosed
US-20230322765-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-10-12 — — US disclosed
WO-2023187182-A1 PYRAZOLOPYRAZINONE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF SANOFI (FR) 2023-10-05 — — WO disclosed
US-11724997-B2 Compounds and compositions for treating conditions associated with APJ receptor activity ANNAPURNA BIO, INC. (US) 2023-08-15 — — US disclosed
US-20230242508-A1 IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2023-08-03 — — US disclosed
EP-3423429-B1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY UNIV DE MONCTON (CA) 2023-07-12 — — EP disclosed
WO-2023115142-A1 ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-06-29 — — WO disclosed
WO-2004024728-A2 PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS GLAXO GROUP LIMITED (GB) 2004-03-25 — — WO disclosed
EP-1334976-A1 Novel phosphine compound, transition metal complex containing said compound as ligand and asymetric synthesis catalyst containing said complex Takasago International Corporation (JP) 2003-08-13 — — EP disclosed
WO-1998043649-A2 AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-10-08 — — WO disclosed
US-5703017-A HERBICIDES, PLANT GROWTH REGULATORS BASF AKTIENGESELLSCHAFT (DE) 1997-12-30 — — US disclosed
CN-1034864-C Maillard reaction inhibitor OTSUKA PHARMA CO LTD (JP) 1997-05-14 — — CN disclosed
US-5422360-A Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-06-06 — — US disclosed
EP-0531812-A1 Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-03-17 — — EP disclosed
CN-1069728-A Maillard reaction inhibitor OTSUKA PHARMA CO LTD (JP) 1993-03-10 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11724997-B2 Compounds and compositions for treating conditions associated with APJ receptor activity APLNR, AGTR1, AGTR2 TAAR1 1160/4885AOC3 4082/4885IDO1 3768/4885
US-20230322765-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH PC, FH, PDK1 TAAR1 3378/4885AOC3 1664/4885IDO1 1180/4885
US-20230242508-A1 IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF IKZF2, IKZF1, IKZF3 TAAR1 4838/4885AOC3 2829/4885IDO1 596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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