SCHEMBL17230489

SCHEMBL17230489

COCCOCc1ccc(OC)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
IDO1 P14902 3/20 0.55
AGXT P21549 2/20 0.55
APP P05067 7/20 0.53
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
MAOB P27338 1/20 0.47
CA12 O43570 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CALM1 P0DP23 1/20 0.46
LTA4H P09960 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45
HTT P42858 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17230490 0.98 APP (0.56) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL8499580 0.94 IDO1 (0.61) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL17230498 0.86 TDP1 (0.54) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL14926412 0.86 APP (0.56) TDP1L3MBTL1APPMAOBALDH1A1
SCHEMBL8368000 0.86 APP (0.70) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL34413 0.84 IDO1 (0.67) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL12462062 0.83 TDP1 (0.56) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL18085581 0.83 PTPN2 (0.41) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL16093231 0.82 APP (0.57) TDP1L3MBTL1IDO1AGXTAPP
SCHEMBL16321948 0.82 APP (0.57) TDP1L3MBTL1IDO1AGXTAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117897439-A Method for screening solvent for extraction of polyvinyl chloride, method for recovering waste material, and recovered polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN claimed
CN-117897440-A Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN claimed
CN-117897439-A Method for screening solvent for extraction of polyvinyl chloride, method for recovering waste material, and recovered polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN disclosed
CN-117897440-A Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN disclosed
US-10662174-B2 BTK inhibitor HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC. (CN) 2020-05-26 US disclosed
US-10175573-B2 Curable composition and color filter FUJIFILM CORPORATION (JP) 2019-01-08 US disclosed
US-20170313683-A1 BTK INHIBITOR HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC. (CN) 2017-11-02 US disclosed
US-20150316844-A1 CURABLE COMPOSITION AND COLOR FILTER FUJIFILM CORPORATION (JP) 2015-11-05 US disclosed
US-20150316844-A1 CURABLE COMPOSITION AND COLOR FILTER FUJIFILM CORPORATION (JP) 2015-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662174-B2 BTK inhibitor BTK, SYK, LYN TDP1 548/4885L3MBTL1 2099/4885IDO1 1360/4885
US-20170313683-A1 BTK INHIBITOR BTK, SYK, LYN TDP1 548/4885L3MBTL1 2099/4885IDO1 1360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.