SCHEMBL34413

SCHEMBL34413

COc1ccc(COCc2ccc(OC)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.67
AGXT P21549 2/20 0.67
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA12 O43570 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58
APP P05067 7/20 0.57
MAOB P27338 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
LTA4H P09960 1/20 0.54
TAAR1 Q96RJ0 1/20 0.54
CALM1 P0DP23 1/20 0.54
ALDH1A1 P00352 1/20 0.52
TP53 P04637 1/20 0.52
CYP3A4 P08684 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1475481 0.97 IDO1 (0.64) IDO1AGXTCA1CA2CA12
Potassium SCHEMBL1477050 0.97 IDO1 (0.64) IDO1AGXTCA1CA2CA12
SCHEMBL11132718 0.93 IDO1 (0.59) IDO1AGXTCA1CA2CA12
SCHEMBL11132720 0.93 LTA4H (0.65) IDO1AGXTCA1CA2CA12
SCHEMBL9292118 0.91 ACHE (0.65) IDO1AGXTCA1CA2APP
SCHEMBL6429953 0.91 LTA4H (0.69) IDO1AGXTCA1CA2APP
SCHEMBL8499580 0.90 IDO1 (0.61) IDO1AGXTCA1CA2CA12
SCHEMBL18320532 0.89 IDO1 (0.55) IDO1AGXTCA1CA2CA12
SCHEMBL1310325 0.89 KMT2A (0.58) IDO1AGXTCA1CA2APP
SCHEMBL52777 0.88 IDO1 (0.59) IDO1AGXTCA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3951 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617759-B2 Modifier of four-membered ring derivative, preparation method and application thereof SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) 2026-05-05 US claimed
US-20260108495-A1 VIRAL INHIBITORS, THE SYNTHESIS THEROF, AND INTERMEDIATES THERETO TAKEDA PHARMACEUTICALS CO (JP) 2026-04-23 US claimed
US-12441741-B2 Ring closing synthesis of macrocyclic MCL-1 inhibitor intermediates AMGEN INC. (US) 2025-10-14 US claimed
US-12435049-B2 Synthesis of vinylic protected alcohol intermediates AMGEN INC. (US) 2025-10-07 US claimed
US-12398117-B2 Heteroarylamidopyridinol derivative and pharmaceutical composition comprising same as active ingredient for prevention or treatment of autoimmune disease INNOVO THERAPEUTICS INC. (KR) 2025-08-26 US claimed
US-20250250260-A1 BRANCHED SUGAR ALCOHOL-BASED COMPOUNDS, AND COMPOSITIONS AND METHODS THEREOF CELLMOSAIC INC (US) 2025-08-07 US claimed
US-12344625-B2 Process for preparing rhenium chelated MAG3 oligonucleotides ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) 2025-07-01 US claimed
EP-4146636-B1 SYNTHESIS OF VINYLIC PROTECTED ALCOHOL INTERMEDIATES AMGEN INC (US) 2025-06-11 EP claimed
CN-119954622-A Vascular endothelial growth factor inhibitor and preparation method and application thereof 香港科技大学 2025-05-09 CN claimed
EP-3971187-B1 INHIBITOR CONTAINING BICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI HANSOH BIOMEDICAL CO LTD (CN) 2025-05-07 EP claimed
US-20080020317-A1 Novel metal nanoparticle and formation of conductive pattern using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-01-24 US claimed
EP-0766660-B1 CYCLOHEXANONE DERIVATIVES, METHOD OF PREPARING THEM AND INTERMEDIATES USED IN THE METHOD SCHERING AG (DE) 1999-12-29 EP claimed
EP-0781293-A4 COMPOSITIONS FOR ENZYME CATALYZED TEMPLATE-INDEPENDENT CREATION OF PHOSPHODIESTER BONDS USING PROTECTED NUCLEOTIDES HIATT ANDREW C ROSE HIATT BIOT (US) 1999-05-26 EP claimed
US-5886233-A Cyclohexanone derivatives, process for their production and intermediate products of the process SCHERING AKTIENGESELLSCHAFT (DE) 1999-03-23 US claimed
EP-0598051-B1 ENZYMATIC METHOD FOR SYNTHESIS OF CARBOHYDRATES PROCUR AB (SE) 1999-03-17 EP claimed
EP-0781293-A1 COMPOSITIONS FOR ENZYME CATALYZED TEMPLATE-INDEPENDENT CREATION OF PHOSPHODIESTER BONDS USING PROTECTED NUCLEOTIDES Hiatt, Andrew C. (US) 1997-07-02 EP claimed
EP-0766660-A1 CYCLOHEXANONE DERIVATIVES, METHOD OF PREPARING THEM AND INTERMEDIATES USED IN THE METHOD SCHERING AKTIENGESELLSCHAFT (DE) 1997-04-09 EP claimed
US-5532147-A Enzymatic method for synthesis of carbohydrates GLYCOREX TRANSPLANTATION AB (PUBL) (SE) 1996-07-02 US claimed
WO-1996007669-A1 COMPOSITIONS FOR ENZYME CATALYZED TEMPLATE-INDEPENDENT CREATION OF PHOSPHODIESTER BONDS USING PROTECTED NUCLEOTIDES ROSE-HIATT BIOTECHNOLOGY PARTNERSHIP (US) 1996-03-14 WO claimed
WO-1996000207-A1 CYCLOHEXANONE DERIVATIVES, METHOD OF PREPARING THEM AND INTERMEDIATES USED IN THE METHOD SCHERING AKTIENGESELLSCHAFT (DE) 1996-01-04 WO claimed