Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.82 |
| ▸ | RECQL | P46063 | 1/20 | 0.82 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.82 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.82 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.82 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.50 |
| ▸ | KIF20A | O95235 | 4/20 | 0.50 |
| ▸ | CLK1 | P49759 | 3/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | IGF2R | P11717 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241869 | 0.90 | SMN1; SMN2 (1.00) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL1959494 | 0.90 | SMN1; SMN2 (1.00) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL31060645 | 0.90 | SMN1; SMN2 (1.00) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL29800237 | 0.90 | SMN1; SMN2 (1.00) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| Hydrochloric Acid SCHEMBL1957339 | 0.89 | SMN1; SMN2 (0.98) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| Hydrochloric Acid SCHEMBL1957337 | 0.89 | SMN1; SMN2 (0.98) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL17232859 | 0.87 | RECQL (0.73) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL6782221 | 0.86 | EGFR (0.82) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL6782228 | 0.86 | EGFR (0.82) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL6782225 | 0.86 | EGFR (0.82) | EGFRSMN1; SMN2RECQLHIF1APDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015166042-A1 | STILBENE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER | DE MONTFORT UNIVERSITY (GB) | 2015-11-05 | — | — | WO | disclosed |