Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.82 |
| ▸ | RECQL | P46063 | 1/20 | 0.82 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.82 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.82 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.82 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.65 |
| ▸ | TUBB | P07437 | 2/20 | 0.65 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.65 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.65 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.65 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.65 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.65 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.65 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.65 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.65 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.65 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.65 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.65 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6782228 | 1.00 | EGFR (0.82) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL6782225 | 1.00 | EGFR (0.82) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL31060645 | 0.90 | SMN1; SMN2 (1.00) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL29800237 | 0.90 | SMN1; SMN2 (1.00) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL1959494 | 0.90 | SMN1; SMN2 (1.00) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL241869 | 0.90 | SMN1; SMN2 (1.00) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| Hydrochloric Acid SCHEMBL1957339 | 0.89 | SMN1; SMN2 (0.98) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| Hydrochloric Acid SCHEMBL1957337 | 0.89 | SMN1; SMN2 (0.98) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL17232854 | 0.86 | EGFR (0.82) | EGFRSMN1; SMN2RECQLHIF1APDGFRB | |
| SCHEMBL17232864 | 0.83 | SMN1; SMN2 (0.77) | EGFRSMN1; SMN2RECQLHIF1APDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015166042-A1 | STILBENE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER | DE MONTFORT UNIVERSITY (GB) | 2015-11-05 | — | — | WO | disclosed |
| US-6677383-B1 | SUPRRESION OF TUMORS CONTAINING OXIDOREDUCTASE ENZYMES, BY CONTACTING THE CELLS WITH ANTITUMOR CHEMICAL INTERMEDIATES SUCH AS 3,4,5-TRIMETHOXY-4'-METHOXYSTILBENE | DE MONTFORT UNIVERSITY (GB) | 2004-01-13 | — | — | US | disclosed |
| US-6346550-B2 | TYROSINE KINASE INHIBITOR; ANTITUMOR AGENT | DE MONTFORT UNIVERSITY (GB) | 2002-02-12 | — | — | US | disclosed |
| US-20010021717-A1 | Hydroxylation activated prodrugs | DE MONTFORT UNIVERSITY | 2001-09-13 | — | — | US | disclosed |
| US-6214886-B1 | INHIBITING GROWTH OF TUMOR CELLS VIA STYRENE-DERIVED PRODRUGS WHICH ARE ACTIVATED BY ACTIVITY OF A HYDROXYLASE | DEMONTFORT UNIVERSITY, THE GATEWAY (GB) | 2001-04-10 | — | — | US | disclosed |
| EP-1051383-A1 | HYDROXYLATION ACTIVATED PRODRUGS | DE MONTFORT UNIVERSITY (GB) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999040056-A1 | HYDROXYLATION ACTIVATED PRODRUGS | DE MONTFORT UNIVERSITY (GB) | 1999-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010021717-A1 | Hydroxylation activated prodrugs | CYP1B1, CYP1A1, CYP1A2 | EGFR 2714/4885SMN1; SMN2 4723/4885RECQL 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.