Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | EGFR | P00533 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | PDGFRB | P09619 | 1/20 | 1.00 |
| ▸ | PDGFRA | P16234 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CLK1 | P49759 | 2/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1959494 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL31060645 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL241869 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| Hydrochloric Acid SCHEMBL1957337 | 0.99 | SMN1; SMN2 (0.98) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| Hydrochloric Acid SCHEMBL1957339 | 0.99 | SMN1; SMN2 (0.98) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL6782221 | 0.90 | EGFR (0.82) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL6782225 | 0.90 | EGFR (0.82) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL6782228 | 0.90 | EGFR (0.82) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL17232854 | 0.90 | EGFR (0.82) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL17232864 | 0.87 | SMN1; SMN2 (0.77) | SMN1; SMN2EGFRRECQLHIF1APDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12281117-B2 | Small molecule immune agonists and immune targeting compounds and application thereof | SHENZHEN UNIVERSITY (CN) | 2025-04-22 | — | — | US | disclosed |
| US-20230364243-A1 | CANCER-SELECTIVE TARGET DEGRADATION BY TARGETING GROUP CAGED PROTACS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| WO-2022165185-A9 | CANCER-SELECTIVE TARGET DEGRADATION BY TARGETING GROUP CAGED PROTACS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2022-12-01 | — | — | WO | disclosed |
| US-20220288207-A1 | PHOTO INDUCED CONTROL OF PROTEIN DESTRUCTION | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2022-09-15 | — | — | US | disclosed |
| WO-2022165185-A1 | CANCER-SELECTIVE TARGET DEGRADATION BY TARGETING GROUP CAGED PROTACS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2022-08-04 | — | — | WO | disclosed |
| WO-2022159687-A1 | PHENOTYPIC ASSAY TO IDENTIFY PROTEIN DEGRADERS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12281117-B2 | Small molecule immune agonists and immune targeting compounds and application thereof | IFNG, IFNAR1, STING1 | SMN1; SMN2 4778/4885EGFR 517/4885RECQL 2022/4885 |
| US-20230364243-A1 | CANCER-SELECTIVE TARGET DEGRADATION BY TARGETING GROUP CAGED PROTACS | ADRM1, MYC, SKP2 | SMN1; SMN2 2925/4885EGFR 268/4885RECQL 2555/4885 |
| US-20220288207-A1 | PHOTO INDUCED CONTROL OF PROTEIN DESTRUCTION | UBE3C, PSMC1, UBE3A | SMN1; SMN2 4208/4885EGFR 2133/4885RECQL 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.