Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.63 |
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16133369 | 0.94 | CASP2 (0.55) | CASP2NAAAFAAHSMN1; SMN2HPGD | |
| SCHEMBL27410517 | 0.91 | CASP2 (0.52) | CASP2NAAAFAAHSMN1; SMN2HPGD | |
| SCHEMBL11912076 | 0.91 | CASP2 (0.66) | CASP2NAAAFAAHHPGDDNM1 | |
| SCHEMBL17624918 | 0.89 | CASP2 (0.59) | CASP2NAAAFAAHSMN1; SMN2DNM1 | |
| SCHEMBL25574266 | 0.89 | CASP2 (0.63) | CASP2NAAAFAAHHPGDDNM1 | |
| SCHEMBL8251628 | 0.89 | CASP2 (0.63) | CASP2NAAAFAAHHPGDDNM1 | |
| SCHEMBL19687365 | 0.88 | CASP2 (0.62) | CASP2NAAAFAAHSMN1; SMN2DNM1 | |
| SCHEMBL17624903 | 0.87 | CASP2 (0.56) | CASP2NAAAFAAHSMN1; SMN2DNM1 | |
| SCHEMBL12508016 | 0.87 | CASP2 (0.61) | CASP2NAAAFAAHHPGDDNM1 | |
| SCHEMBL15888712 | 0.87 | SMN1; SMN2 (0.60) | CASP2NAAAFAAHSMN1; SMN2DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137898-B1 | FLUORESCENT MOLECULAR SENSOR FOR TARGETING CHANGES IN PROTEIN SURFACES, AND METHODS OF USE THEREOF | YEDA RES & DEV (IL) | 2023-09-20 | — | — | EP | disclosed |
| WO-2020245814-A1 | ARTIFICIAL RECEPTORS, RECOMBINANT CELLS COMPRISING THEREOF, METHODS FOR THEIR PREPARATION, AND METHOD OF USING THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2020-12-10 | — | — | WO | disclosed |
| US-20170045522-A1 | FLUORESCENT MOLECULAR SENSOR FOR TARGETING CHANGES IN PROTEIN SURFACES, AND METHODS OF USE THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-02-16 | — | — | US | disclosed |
| WO-2015166491-A2 | FLUORESCENT MOLECULAR SENSOR FOR TARGETING CHANGES IN PROTEIN SURFACES, AND METHODS OF USE THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2015-11-05 | — | — | WO | disclosed |