Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17624918 | 0.95 | CASP2 (0.59) | CASP2SMN1; SMN2NAAAFAAHTSHR | |
| SCHEMBL17624739 | 0.95 | SMN1; SMN2 (0.61) | CASP2SMN1; SMN2NAAAFAAHTSHR | |
| SCHEMBL19687365 | 0.93 | CASP2 (0.62) | CASP2SMN1; SMN2NAAAFAAHEPHX2 | |
| SCHEMBL15888712 | 0.89 | SMN1; SMN2 (0.60) | CASP2SMN1; SMN2NAAAFAAHTSHR | |
| SCHEMBL17233451 | 0.87 | CASP2 (0.63) | CASP2SMN1; SMN2NAAAFAAHEPHX2 | |
| SCHEMBL14235690 | 0.86 | SMN1; SMN2 (0.60) | CASP2SMN1; SMN2NAAAFAAHTSHR | |
| SCHEMBL26706549 | 0.86 | SMN1; SMN2 (0.49) | CASP2SMN1; SMN2NAAAFAAHTSHR | |
| SCHEMBL13492963 | 0.85 | SMN1; SMN2 (0.59) | CASP2SMN1; SMN2NAAAFAAHTSHR | |
| SCHEMBL16133369 | 0.85 | CASP2 (0.55) | CASP2SMN1; SMN2NAAAFAAHTSHR | |
| SCHEMBL9633440 | 0.84 | CASP2 (0.51) | CASP2SMN1; SMN2NAAAFAAHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044585-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |