SCHEMBL1723352

SCHEMBL1723352

CCONC(=O)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.65
RAB9A P51151 7/20 0.65
ALDH1A1 P00352 1/20 0.55
POLB P06746 1/20 0.55
MAPT P10636 1/20 0.55
KMT2A Q03164 1/20 0.55
HDAC3 O15379 3/20 0.51
HDAC1 Q13547 3/20 0.51
HDAC7 Q8WUI4 3/20 0.51
HDAC2 Q92769 3/20 0.51
HDAC8 Q9BY41 3/20 0.51
HDAC6 Q9UBN7 3/20 0.51
HDAC4 P56524 2/20 0.51
HDAC10 Q969S8 2/20 0.51
HDAC11 Q96DB2 2/20 0.51
HDAC9 Q9UKV0 2/20 0.51
HDAC5 Q9UQL6 2/20 0.51
SMN1; SMN2 Q16637 3/20 0.50
GAA P10253 2/20 0.50
CA12 O43570 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27776089 0.93 RAB9A (0.57) NPC1RAB9AALDH1A1POLBMAPT
SCHEMBL5385289 0.85 NPC1 (0.61) NPC1RAB9AALDH1A1POLBMAPT
Hydrochloric Acid SCHEMBL27792112 0.83 NPC1 (0.59) NPC1RAB9AALDH1A1POLBMAPT
SCHEMBL27755279 0.83 AKR1C3 (0.50) NPC1RAB9AALDH1A1MAPTKMT2A
SCHEMBL27702882 0.82 RAB9A (0.69) NPC1RAB9AALDH1A1POLBMAPT
SCHEMBL13724578 0.82 LMNA (0.56) NPC1RAB9AALDH1A1POLBMAPT
SCHEMBL27769392 0.82 PARP10 (0.56) NPC1RAB9AALDH1A1MAPTKMT2A
SCHEMBL5092287 0.82 HDAC3 (0.61) NPC1RAB9AALDH1A1POLBMAPT
SCHEMBL11105039 0.81 HDAC3 (0.54) NPC1RAB9AALDH1A1POLBMAPT
SCHEMBL28401199 0.81 NPC1 (0.61) NPC1RAB9AALDH1A1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110204438-B Method for separating succinic acid and glutaric acid 浙江科技学院 2021-10-22 CN claimed
EP-2926127-B1 AIR REMOVAL TEST STRIP AMERICAN STERILIZER CO (US) 2020-05-06 EP claimed
CN-110204438-A A kind of separation method of succinic acid, glutaric acid 浙江科技学院 2019-09-06 CN claimed
CN-106365800-B A kind of matrix for silk ball bacteria cultivation 福建容益菌业科技研发有限公司 2019-05-17 CN claimed
CN-107523505-A A kind of matrix for silk ball bacteria cultivation and preparation method thereof 杭州千岛湖兴宝菇业专业合作社 2017-12-29 CN claimed
CN-106365800-A Matrix for cultivating Sparassis crispa 福建容益菌业科技研发有限公司 2017-02-01 CN claimed
CN-106305143-A Carrier used for sparassis crispa cultivation 张伟峰 2017-01-11 CN claimed
EP-2926127-A1 AIR REMOVAL TEST STRIP Dana Products, Inc. (US) 2015-10-07 EP claimed
CN-104919314-A Air removal test strip DANA PRODUCTS INC 2015-09-16 CN claimed
CN-102143961-B Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity NEURAXON INC 2014-11-05 CN claimed
CN-102014912-A Combination therapy 238 ASTRAZENECA AB 2011-04-13 CN claimed
CN-101309922-A Amino-aza-adamantane derivatives and methods of use ABBOTT LAB (US) 2008-11-19 CN claimed
CN-101267825-A Benzodiazepine derivatives for treating hepatitis C infection ARROW THERAPEUTICS LTD (GB) 2008-09-17 CN claimed
CN-1646125-A Substituted pyridones as modulators of P38MAP kinase PHARMACIA CORP (US) 2005-07-27 CN claimed
EP-0934264-A1 PYRROLIDINYL AND PYRROLINYL ETHYLAMINE COMPOUNDS AS KAPPA AGONISTS PFIZER INC. (US) 1999-08-11 EP claimed
WO-1998012177-A1 PYRROLIDINYL AND PYRROLINYL ETHYLAMINE COMPOUNDS AS KAPPA AGONISTS PFIZER INC. (JP) 1998-03-26 WO claimed
US-5663029-A DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0648506-A1 Sterility indicator device PyMaH Corporation (US) 1995-04-19 EP claimed
US-5378430-A Steam sterilization process monitor PYMAH CORPORATION (US) 1995-01-03 US claimed
US-3981683-A FOR USE IN AUTOCLAVE BIO-MEDICAL SCIENCES, INC. (US) 1976-09-21 US claimed