SCHEMBL1723576

SCHEMBL1723576

CCCCOC(=O)c1c(CC(C)C)sc(S(N)(=O)=O)c1-c1ccc(Cn2ccnc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 20/20 0.57
AGTR1 P30556 1/20 0.57
CYP2C9 P11712 1/20 0.50
CYP2B6 P20813 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6623560 0.84 AGTR2 (0.58) AGTR2AGTR1CYP2C9CYP2B6
SCHEMBL4316720 0.83 AGTR2 (0.61) AGTR2AGTR1CYP2C9CYP2B6
SCHEMBL27973549 0.82 AGTR2 (0.48) AGTR2AGTR1CYP2C9CYP2B6
SCHEMBL557059 0.81 AGTR2 (0.55) AGTR2AGTR1CYP2C9CYP2B6
SCHEMBL26127636 0.80 AGTR2 (0.72) AGTR2AGTR1CYP2C9CYP2B6
SCHEMBL27985940 0.80 AGTR2 (0.37) AGTR2AGTR1
SCHEMBL26128256 0.80 AGTR2 (0.49) AGTR2AGTR1
SCHEMBL31476812 0.80 AGTR2 (0.71) AGTR2AGTR1CYP2C9CYP2B6
SCHEMBL7123182 0.78 AGTR2 (0.39) AGTR2AGTR1
SCHEMBL27973603 0.77 AGTR2 (0.43) AGTR2AGTR1CYP2C9CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119300823-A Use of cloth Luo Tide for treating idiopathic pulmonary fibrosis 维科尔药物公司 2025-01-10 CN claimed
WO-2024133942-A1 A METHOD OF TREATING A PATIENT DIAGNOSED WITH AN INTERSTITIAL LUNG DISEASE VICORE PHARMA AB (SE) 2024-06-27 WO claimed
WO-2023152503-A1 USE OF BULOXIBUTID FOR THE TREATMENT OF IDIOPATHIC PULMONARY FIBROSIS VICORE PHARMA AB (SE) 2023-08-17 WO claimed
EP-4138789-A1 NEW DELAYED RELEASE COMPOSITION FOR PERORAL ADMINISTRATION Vicore Pharma AB (SE) 2023-03-01 EP claimed
EP-4138788-A1 NEW CAPSULE COMPOSITION FOR PERORAL ADMINISTRATION Vicore Pharma AB (SE) 2023-03-01 EP claimed
EP-4138790-A1 NEW DRY POWDER COMPOSITION FOR PERORAL ADMINISTRATION Vicore Pharma AB (SE) 2023-03-01 EP claimed
CN-115605201-A New use of angiotensin II type 2 receptor agonists 维科尔药物公司(SE) 2023-01-13 CN claimed
WO-2021214487-A1 NEW DELAYED RELEASE COMPOSITION FOR PERORAL ADMINISTRATION VICORE PHARMA AB (SE) 2021-10-28 WO claimed
WO-2021214486-A1 NEW CAPSULE COMPOSITION FOR PERORAL ADMINISTRATION VICORE PHARMA AB (SE) 2021-10-28 WO claimed
WO-2021214488-A1 NEW DRY POWDER COMPOSITION FOR PERORAL ADMINISTRATION VICORE PHARMA AB (SE) 2021-10-28 WO claimed
EP-3876902-A1 NEW COMPOSITION COMPRISING AMORPHOUS NANOPOROUS SILICA PARTICLES Vicore Pharma AB (SE) 2021-09-15 EP claimed
WO-2021105695-A1 NEW USE OF ANGIOTENSIN II RECEPTOR AGONIST VICORE PHARMA AB (SE) 2021-06-03 WO claimed
WO-2019183513-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF MUSCULAR DYSTROPHY UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2019-09-26 WO claimed
WO-2019183513-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF MUSCULAR DYSTROPHY UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2019-09-26 WO disclosed
EP-3229839-A1 NEW METHODS AND USES Vicore Pharma AB (SE) 2017-10-18 EP disclosed
WO-2016092329-A1 NEW METHODS AND USES VICORE PHARMA AB (SE) 2016-06-16 WO disclosed
EP-1869023-B1 NEW TRICYCLIC ANGIOTENSIN II AGONISTS VICORE PHARMA AB (SE) 2012-01-11 EP disclosed
US-8080571-B2 Tricyclic angiotensin II agonists VICORE PHARMA AB (SE) 2011-12-20 US disclosed
US-20090042931-A1 Tricyclic Angiotensin II Agonists VICORE PHARMA AB (SE) 2009-02-12 US disclosed
US-20040167176-A1 Tricyclic compounds useful as angiotensin II agonists VICORE PHARMA AB (SE) 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167176-A1 Tricyclic compounds useful as angiotensin II agonists AGTR1, AGTR2, NPY2R AGTR2 2/4885AGTR1 1/4885CYP2C9 1541/4885
US-20090042931-A1 Tricyclic Angiotensin II Agonists AGTR2, AGTR1, NPY4R AGTR2 1/4885AGTR1 2/4885CYP2C9 1127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.