Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.77 |
| ▸ | TSHR | P16473 | 4/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.77 |
| ▸ | THRB | P10828 | 2/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.77 |
| ▸ | CASP1 | P29466 | 1/20 | 0.77 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13776661 | 1.00 | ALDH1A1 (0.77) | ALDH1A1TSHRTDP1CYP3A4ALOX15 | |
| SCHEMBL94935 | 1.00 | ALDH1A1 (0.77) | ALDH1A1TSHRTDP1CYP3A4ALOX15 | |
| SCHEMBL17821990 | 0.98 | ALDH1A1 (0.74) | ALDH1A1TSHRTDP1CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL17710389 | 0.98 | ALDH1A1 (0.74) | ALDH1A1TSHRTDP1CYP3A4ALOX15 | |
| Nitrogen SCHEMBL10788887 | 0.96 | ALDH1A1 (0.71) | ALDH1A1TSHRTDP1CYP3A4ALOX15 | |
| SCHEMBL17822023 | 0.96 | TSHR (0.71) | ALDH1A1TSHRTDP1CYP3A4ALOX15 | |
| SCHEMBL17046082 | 0.96 | TSHR (0.71) | ALDH1A1TSHRTDP1CYP3A4ALOX15 | |
| SCHEMBL93902 | 0.92 | ALDH1A1 (0.72) | ALDH1A1TSHRTDP1CYP3A4ALOX15 | |
| SCHEMBL17046159 | 0.92 | TSHR (0.65) | ALDH1A1TSHRTDP1CYP3A4ALOX15 | |
| SCHEMBL49805 | 0.87 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |