SCHEMBL17821990

SCHEMBL17821990

CCC(C)Nc1ccccc1.[SiH4]

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.74
TSHR P16473 4/20 0.74
TDP1 Q9NUW8 3/20 0.74
CYP3A4 P08684 3/20 0.74
ALOX15 P16050 3/20 0.74
HSD17B10 Q99714 3/20 0.74
HIF1A Q16665 2/20 0.74
THRB P10828 2/20 0.74
L3MBTL1 Q9Y468 2/20 0.74
SMN1; SMN2 Q16637 2/20 0.74
TP53 P04637 1/20 0.74
HSP90AA1 P07900 1/20 0.74
CASP1 P29466 1/20 0.74
ALOX12 P18054 2/20 0.55
MAPK1 P28482 1/20 0.55
LMNA P02545 1/20 0.48
RECQL P46063 1/20 0.48
ATM Q13315 1/20 0.48
ELANE P08246 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13776661 0.98 ALDH1A1 (0.77) ALDH1A1TSHRTDP1CYP3A4ALOX15
SCHEMBL94935 0.98 ALDH1A1 (0.77) ALDH1A1TSHRTDP1CYP3A4ALOX15
SCHEMBL172358 0.98 ALDH1A1 (0.77) ALDH1A1TSHRTDP1CYP3A4ALOX15
Hydrochloric Acid SCHEMBL17710389 0.95 ALDH1A1 (0.74) ALDH1A1TSHRTDP1CYP3A4ALOX15
SCHEMBL17046082 0.93 TSHR (0.71) ALDH1A1TSHRTDP1CYP3A4ALOX15
Nitrogen SCHEMBL10788887 0.93 ALDH1A1 (0.71) ALDH1A1TSHRTDP1CYP3A4ALOX15
SCHEMBL17822023 0.93 TSHR (0.71) ALDH1A1TSHRTDP1CYP3A4ALOX15
SCHEMBL93902 0.90 ALDH1A1 (0.72) ALDH1A1TSHRTDP1CYP3A4ALOX15
SCHEMBL17046159 0.90 TSHR (0.65) ALDH1A1TSHRTDP1CYP3A4ALOX15
SCHEMBL49805 0.85 ALDH1A1 (1.00) ALDH1A1TSHRTDP1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3535436-B1 PRECURSORS AND FLOWABLE CVD METHODS FOR MAKING LOW-K FILMS TO FILL SURFACE FEATURES VERSUM MAT US LLC (US) 2021-05-12 EP claimed
EP-3535436-B1 PRECURSORS AND FLOWABLE CVD METHODS FOR MAKING LOW-K FILMS TO FILL SURFACE FEATURES VERSUM MAT US LLC (US) 2021-05-12 EP disclosed
EP-3395822-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME Versum Materials US, LLC (US) 2018-10-31 EP disclosed
US-9758534-B2 Organoaminosilanes and methods for making same VERSUM MATERIALS US, LLC (US) 2017-09-12 US disclosed
US-20160168169-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160168169-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME DDAH1, IDUA, DDT ALDH1A1 418/4885TSHR 3989/4885TDP1 761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.