Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4493980 | 0.87 | GAA (0.53) | GAAMAPTPKMMETGPBAR1 | |
| SCHEMBL9189951 | 0.78 | KMT2A (0.44) | MAPTLMNAKMT2ANAPRTMEN1 | |
| Ammonia Solution, Strong SCHEMBL9190338 | 0.77 | KMT2A (0.43) | MAPTLMNAKMT2ANAPRTMEN1 | |
| SCHEMBL30585396 | 0.77 | KMT2A (0.43) | MAPTLMNAKMT2ANAPRTMEN1 | |
| SCHEMBL31098672 | 0.75 | GAA (0.52) | GAAMAPTPKMGPBAR1LMNA | |
| SCHEMBL4522913 | 0.74 | LTA4H (0.49) | MAPTLMNAKMT2ANAPRTPOLB | |
| SCHEMBL5935115 | 0.74 | MLYCD (0.67) | MAPTKMT2APOLBGRM1MLYCD | |
| Hydrochloric Acid SCHEMBL2163648 | 0.73 | LTA4H (0.47) | MAPTLMNAKMT2ANAPRTPOLB | |
| SCHEMBL30370193 | 0.73 | POLB (0.76) | GAAMAPTPKMGPBAR1LMNA | |
| SCHEMBL2797998 | 0.72 | MLNR (0.47) | GAAMAPTPKMGPBAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2942346-A1 | PYRIDINE- AND PYRIMIDINECARBOXAMIDES AS CXCR2 MODULATORS | Syntrix Biosystems, Inc. (US) | 2015-11-11 | — | — | EP | disclosed |