Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976085 | 0.81 | ALDH1A1 (0.65) | KDM4EHSD17B10NPC1RAB9AMAPT | |
| SCHEMBL28632938 | 0.80 | CYP3A4 (0.71) | KDM4EHSD17B10NPC1RAB9AMAPT | |
| SCHEMBL9137058 | 0.76 | KDM4E (0.56) | KDM4EHSD17B10NPC1RAB9AMAPT | |
| SCHEMBL8493104 | 0.75 | KDM4E (0.52) | KDM4EHSD17B10NPC1RAB9AMAPT | |
| SCHEMBL8494882 | 0.75 | NQO1 (0.52) | KDM4EHSD17B10NPC1RAB9AMAPT | |
| SCHEMBL31670262 | 0.74 | MAPT (0.64) | KDM4EHSD17B10MAPTTP53GAA | |
| SCHEMBL620145 | 0.74 | MAPT (0.64) | KDM4EHSD17B10MAPTTP53GAA | |
| SCHEMBL5303760 | 0.74 | KDM4E (0.50) | KDM4EHSD17B10NPC1RAB9AMAPT | |
| SCHEMBL20886870 | 0.73 | MAPT (0.53) | KDM4EHSD17B10MAPTTP53GAA | |
| SCHEMBL30087046 | 0.73 | MAPT (0.53) | KDM4EHSD17B10MAPTTP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160143878-A1 | ANTIBACTERIAL AGENT | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2016-05-26 | — | — | US | disclosed |
| US-20150322033-A1 | ANTIBACTERIAL AGENT | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160143878-A1 | ANTIBACTERIAL AGENT | MRPL21, Q6ZSR9, NQO2 | KDM4E 3210/4885HSD17B10 725/4885NPC1 2966/4885 |
| US-20150322033-A1 | ANTIBACTERIAL AGENT | Q6ZSR9, MRPL21, NQO2 | KDM4E 3156/4885HSD17B10 805/4885NPC1 3145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.