Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 8/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31670262 | 1.00 | MAPT (0.64) | MAPTALOX15CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL30087046 | 0.81 | MAPT (0.53) | MAPTALOX15CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL20886870 | 0.81 | MAPT (0.53) | MAPTALOX15CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL31398703 | 0.79 | AR (0.55) | MAPTALOX15CYP1A2SMN1; SMN2KDM4E | |
| Noreugenin SCHEMBL29370130 | 0.78 | PTGS2 (0.71) | MAPTALOX15CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL29854712 | 0.78 | AR (0.58) | MAPTALOX15CYP1A2SMN1; SMN2KDM4E | |
| Noreugenin SCHEMBL168822 | 0.78 | PTGS2 (0.71) | MAPTALOX15CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL13717866 | 0.78 | AR (0.58) | MAPTALOX15CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL15920417 | 0.77 | POLH (0.58) | MAPTALOX15CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL14752570 | 0.77 | ALOX15 (0.57) | MAPTALOX15CYP1A2SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | SENOMYX, INC. (US) | 2019-04-02 | — | — | US | claimed |
| CN-106107406-A | Improve the method for the stability of sweetness enhancers and comprise the compositions of stable sweetness enhancers | 赛诺米克斯公司 | 2016-11-16 | — | — | CN | claimed |
| US-20150245642-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED | 2015-09-03 | — | — | US | claimed |
| EP-2603098-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | Senomyx, Inc. (US) | 2013-06-19 | — | — | EP | claimed |
| CN-103153096-A | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | SENOMYX INC | 2013-06-12 | — | — | CN | claimed |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | US | claimed |
| WO-2012021837-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | WO | claimed |
| EP-2603098-B1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED (US) | 2025-08-06 | — | — | EP | disclosed |
| CN-115724816-B | Chromone crystal form in mangrove-derived fungi and preparation and application thereof | 海南师范大学 | 2023-11-24 | — | — | CN | disclosed |
| CN-115490661-B | Antioxidant active compound in mangrove-derived fungi and preparation method thereof | 海南师范大学 | 2023-09-08 | — | — | CN | disclosed |
| CN-115724816-A | Crystal form of chromone in mangrove-derived fungi, preparation and application thereof | 海南师范大学 | 2023-03-03 | — | — | CN | disclosed |
| CN-115490661-A | Antioxidant active compound in mangrove-derived fungi and preparation method thereof | 海南师范大学 | 2022-12-20 | — | — | CN | disclosed |
| US-20210401840-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS AG (CH) | 2021-12-30 | — | — | US | disclosed |
| EP-1508327-A1 | Use of chromen-4-one derivatives for the care of skin and hair | MERCK PATENT GmbH (DE) | 2005-02-23 | — | — | EP | disclosed |
| EP-0430693-B1 | Pyrimidinedione derivative compounds, method for preparing same, and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS (JP) | 1995-05-31 | — | — | EP | disclosed |
| US-5114941-A | PYRIMIDINEDIONE DERIVATIVE COMPOUNDS, METHOD FOR PREPARING SAME, AND ANTIARRYTHMIC AGENTS CONTAINING SAME | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-19 | — | — | US | disclosed |
| EP-0430693-A2 | Pyrimidinedione derivative compounds, method for preparing same, and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-06-05 | — | — | EP | disclosed |
| US-4105781-A | ANTIALLERGENS FOR TREATMENT OF ASTHMA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1978-08-08 | — | — | US | disclosed |
| US-4049664-A | ANTIALLERGENS, ANTIASTHMATICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-09-20 | — | — | US | disclosed |
| US-3965122-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | MAPT 1864/4885ALOX15 2796/4885CYP1A2 4854/4885 |
| US-20210401840-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | PRKCA, PRKCH, PRKCB | MAPT 1946/4885ALOX15 3919/4885CYP1A2 4618/4885 |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | MAPT 1864/4885ALOX15 2796/4885CYP1A2 4854/4885 |
| US-20150245642-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | MAPT 1864/4885ALOX15 2796/4885CYP1A2 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.