Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.61 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.61 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15705823 | 0.93 | PLCG1 (0.71) | MAPK1PLCG1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL17245020 | 0.88 | PLCG1 (0.64) | MAPK1PLCG1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL11080633 | 0.87 | ALDH1A1 (0.64) | MAPK1PLCG1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL11182339 | 0.86 | TDP1 (0.81) | MAPK1ALDH1A1KMT2AHSD17B10TDP1 | |
| SCHEMBL11078627 | 0.86 | KMT2A (0.67) | MAPK1PLCG1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL11078633 | 0.86 | KMT2A (0.67) | MAPK1PLCG1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL9741414 | 0.85 | DRD2 (0.60) | MAPK1PLCG1ALDH1A1KMT2ATDP1 | |
| SCHEMBL9741416 | 0.85 | DRD2 (0.60) | MAPK1PLCG1ALDH1A1KMT2ATDP1 | |
| SCHEMBL9807357 | 0.85 | KMT2A (0.64) | MAPK1PLCG1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL9807370 | 0.85 | KMT2A (0.64) | MAPK1PLCG1ALDH1A1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10059722-B2 | Cephalosporin derivatives and methods of use | UNIVERSITY OF KANSAS (US) | 2018-08-28 | — | — | US | disclosed |
| US-20150322087-A1 | CEPHALOSPORIN DERIVATIVES AND METHODS OF USE | UNIVERSITY OF KANSAS | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10059722-B2 | Cephalosporin derivatives and methods of use | CNDP2, CLSPN, PEPD | MAPK1 3898/4885PLCG1 3029/4885ALDH1A1 1927/4885 |
| US-20150322087-A1 | CEPHALOSPORIN DERIVATIVES AND METHODS OF USE | CNDP2, CLSPN, PEPD | MAPK1 3898/4885PLCG1 3029/4885ALDH1A1 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.