SCHEMBL17239083

SCHEMBL17239083

C=C[SiH](O[SiH](C=C)c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
AKT1 P31749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL580082 0.81 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL485788 0.81 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL28034026 0.78 ALDH1A1 (0.31) ALDH1A1TSHRAKT1
SCHEMBL27840477 0.78 MAPK1 (0.32) ALDH1A1TSHR
SCHEMBL11493076 0.78 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL17239075 0.76 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL674277 0.76 RELA (0.32) ALDH1A1TSHR
SCHEMBL21065532 0.76 AKT1 (0.38) ALDH1A1TSHRAKT1
SCHEMBL18145369 0.74
SCHEMBL21065534 0.73 AKT1 (0.35) ALDH1A1TSHRAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9512272-B2 Curable composition containing silicone, and cured product thereof CENTRAL GLASS COMPANY, LIMITED (JP) 2016-12-06 US disclosed
US-20150322211-A1 Curable Composition Containing Silicone, and Cured Product Thereof CENTRAL GLASS COMPANY, LIMITED (JP) 2015-11-12 US disclosed