SCHEMBL17239097

SCHEMBL17239097

C=C([SiH3])c1ccccc1OCC

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 2/20 0.53
ALDH1A1 P00352 5/20 0.51
HPGD P15428 1/20 0.51
HSD17B10 Q99714 1/20 0.51
MAPT P10636 3/20 0.46
GAA P10253 2/20 0.46
MAPK1 P28482 1/20 0.46
L3MBTL1 Q9Y468 4/20 0.46
GLA P06280 1/20 0.46
NPSR1 Q6W5P4 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
KDM4E B2RXH2 2/20 0.44
HTT P42858 1/20 0.44
LMNA P02545 2/20 0.44
KCNK3 O14649 1/20 0.43
KCNK9 Q9NPC2 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14956512 0.85 LMNA (0.47) ALDH1A1MAPTL3MBTL1NPSR1MEN1
SCHEMBL5831791 0.84 HCRTR1 (0.41) HCRTR1ALDH1A1HPGDHSD17B10MAPT
SCHEMBL4952648 0.82 HCRTR1 (0.54) HCRTR1ALDH1A1HPGDHSD17B10MAPT
Ammonia Solution, Strong SCHEMBL8638675 0.81 HCRTR1 (0.53) HCRTR1ALDH1A1HPGDHSD17B10MAPT
SCHEMBL13866658 0.81 HCRTR1 (0.53) HCRTR1ALDH1A1HPGDHSD17B10MAPT
SCHEMBL2490797 0.79 HCRTR1 (0.59) HCRTR1ALDH1A1HPGDHSD17B10MAPT
SCHEMBL2117236 0.78 HCRTR1 (0.58) HCRTR1ALDH1A1HPGDHSD17B10MAPT
SCHEMBL17239064 0.78 CA1 (0.50) HPGDHTTKCNK3KCNK9RAB9A
SCHEMBL10573700 0.77 HCRTR1 (0.62) HCRTR1ALDH1A1HPGDHSD17B10MAPT
SCHEMBL24285505 0.77 HCRTR1 (0.49) HCRTR1ALDH1A1HPGDHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9512272-B2 Curable composition containing silicone, and cured product thereof CENTRAL GLASS COMPANY, LIMITED (JP) 2016-12-06 US disclosed
US-20150322211-A1 Curable Composition Containing Silicone, and Cured Product Thereof CENTRAL GLASS COMPANY, LIMITED (JP) 2015-11-12 US disclosed