Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952648 | 0.82 | HCRTR1 (0.54) | HCRTR1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL17239097 | 0.81 | HCRTR1 (0.53) | HCRTR1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL990 | 0.81 | HCRTR1 (0.62) | HCRTR1ALDH1A1HPGDHSD17B10MAPT | |
| Ammonia Solution, Strong SCHEMBL8638675 | 0.81 | HCRTR1 (0.53) | HCRTR1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL2490797 | 0.79 | HCRTR1 (0.59) | HCRTR1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL335970 | 0.78 | LMNA (0.71) | HCRTR1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL30292656 | 0.78 | LMNA (0.71) | HCRTR1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL2124599 | 0.78 | HCRTR1 (0.50) | HCRTR1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL2124597 | 0.78 | HCRTR1 (0.50) | HCRTR1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL16933973 | 0.78 | CA1 (0.50) | LMNAHTTTP53TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517895-B2 | Synthetic diazonamides | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-04-14 | — | — | US | disclosed |