Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12201250 | 0.92 | CYP2D6 (0.39) | LMNACYP2D6CYP2C19L3MBTL1ALDH1A1 | |
| SCHEMBL1723479 | 0.78 | CYP2D6 (0.66) | LMNACYP2D6CYP2C19L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1712098 | 0.77 | CYP2D6 (0.64) | LMNACYP2D6CYP2C19L3MBTL1ALDH1A1 | |
| Bromide SCHEMBL1712889 | 0.77 | CYP2D6 (0.64) | LMNACYP2D6CYP2C19L3MBTL1ALDH1A1 | |
| SCHEMBL1724177 | 0.75 | THRB (0.38) | LMNAALDH1A1TSHRSMN1; SMN2CES2 | |
| Acetic Acid SCHEMBL1712555 | 0.74 | CYP2D6 (0.60) | LMNACYP2D6CYP2C19L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11604018 | 0.73 | CYP2D6 (0.59) | LMNACYP2D6CYP2C19L3MBTL1ALDH1A1 | |
| SCHEMBL1724231 | 0.72 | THRB (0.35) | LMNACYP2D6ALDH1A1TSHRNPSR1 | |
| Sulfuric Acid SCHEMBL2183925 | 0.71 | CYP2D6 (0.56) | LMNACYP2D6CYP2C19L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1712399 | 0.71 | THRB (0.34) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2320854-B1 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2012-01-18 | — | — | EP | disclosed |
| EP-2320854-B1 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2012-01-18 | — | — | EP | disclosed |
| US-20110162671-A1 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2011-07-07 | — | — | US | disclosed |
| WO-2010054981-A2 | COMBINATION OF CATIONIC BLEACH ACTIVATORS AND DYES | HENKEL AG & CO. KGAA (DE) | 2010-05-20 | — | — | WO | disclosed |
| WO-2010029006-A2 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2010-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110162671-A1 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | KRT18, CBR3, ACOX3 | LMNA 631/4885CYP2D6 758/4885CYP2C19 1434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.