Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 7/20 | 0.68 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.68 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.68 |
| ▸ | YES1 | P07947 | 2/20 | 0.68 |
| ▸ | PIM1 | P11309 | 1/20 | 0.68 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | WNT1 | P04628 | 4/20 | 0.54 |
| ▸ | GSK3B | P49841 | 4/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.54 |
| ▸ | MET | P08581 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MST1R | Q04912 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15884535 | 0.91 | MAPK1 (0.67) | MAPK1AURKBNTRK1YES1PIM1 | |
| SCHEMBL17251852 | 0.88 | MAPK1 (0.60) | MAPK1AURKBNTRK1YES1PIM1 | |
| SCHEMBL21708381 | 0.88 | MAPK1 (0.68) | MAPK1AURKBNTRK1YES1PIM1 | |
| SCHEMBL17251871 | 0.85 | MAPK1 (0.60) | MAPK1AURKBNTRK1YES1PIM1 | |
| SCHEMBL17251849 | 0.84 | MAPK1 (0.59) | MAPK1AURKBNTRK1YES1PIM1 | |
| SCHEMBL1933387 | 0.81 | MAPK1 (1.00) | MAPK1AURKBNTRK1YES1PIM1 | |
| SCHEMBL15884825 | 0.81 | MAPK1 (0.62) | MAPK1AURKBNTRK1YES1PIM1 | |
| SCHEMBL15883804 | 0.81 | MAPK1 (0.62) | MAPK1AURKBNTRK1YES1PIM1 | |
| SCHEMBL19441788 | 0.80 | MAPK1 (0.62) | MAPK1AURKBNTRK1YES1PIM1 | |
| SCHEMBL14681532 | 0.80 | AURKB (0.68) | MAPK1AURKBNTRK1YES1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |
| US-9783536-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| US-9783536-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| EP-2944637-A1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM Corporation (JP) | 2015-11-18 | — | — | EP | disclosed |
| US-20150322063-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2015-11-12 | — | — | US | disclosed |
| US-20150322063-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322063-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | NPM1, NAP1L1, REN | MAPK1 149/4885AURKB 3921/4885NTRK1 3350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.