Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.56 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12272715 | 1.00 | S1PR1 (0.56) | S1PR1S1PR3S1PR4S1PR5LPAR3 | |
| SCHEMBL15500035 | 1.00 | S1PR1 (0.56) | S1PR1S1PR3S1PR4S1PR5LPAR3 | |
| SCHEMBL6762713 | 0.94 | GSTM2 (0.57) | S1PR1S1PR3S1PR4S1PR5GSTM2 | |
| SCHEMBL4222844 | 0.91 | FABP3 (0.50) | S1PR1S1PR3S1PR4S1PR5LPAR3 | |
| SCHEMBL6510371 | 0.91 | S1PR1 (0.48) | S1PR1S1PR3S1PR4S1PR5LPAR3 | |
| SCHEMBL6704299 | 0.91 | S1PR1 (0.48) | S1PR1S1PR3S1PR4S1PR5LPAR3 | |
| SCHEMBL6759054 | 0.89 | GSTM2 (0.56) | S1PR1S1PR3S1PR4S1PR5GSTM2 | |
| SCHEMBL1535864 | 0.88 | SMN1; SMN2 (0.61) | S1PR1S1PR3S1PR4S1PR5SMN1; SMN2 | |
| SCHEMBL1436399 | 0.88 | SMN1; SMN2 (0.61) | S1PR1S1PR3S1PR4S1PR5SMN1; SMN2 | |
| SCHEMBL1535067 | 0.88 | SMN1; SMN2 (0.61) | S1PR1S1PR3S1PR4S1PR5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150323495-A1 | NON-AQUEOUS MICROCHIP ELECTROPHORESIS FOR CHARACTERIZATION OF LIPID BIOMARKERS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2015-11-12 | — | — | US | disclosed |