Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.48 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.44 |
| ▸ | SELP | P16109 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510371 | 1.00 | S1PR1 (0.48) | S1PR1S1PR3S1PR4S1PR5FABP3 | |
| SCHEMBL2360799 | 0.96 | S1PR1 (0.53) | S1PR1S1PR3S1PR4S1PR5FABP3 | |
| SCHEMBL4222844 | 0.94 | FABP3 (0.50) | S1PR1S1PR3S1PR4S1PR5FABP3 | |
| SCHEMBL4419953 | 0.93 | S1PR1 (0.47) | S1PR1S1PR3S1PR4S1PR5FABP3 | |
| SCHEMBL29523085 | 0.92 | FABP3 (0.59) | S1PR1S1PR3S1PR4S1PR5FABP3 | |
| SCHEMBL15500035 | 0.91 | S1PR1 (0.56) | S1PR1S1PR3S1PR4S1PR5GSTM2 | |
| SCHEMBL17240248 | 0.91 | S1PR1 (0.56) | S1PR1S1PR3S1PR4S1PR5GSTM2 | |
| SCHEMBL12272715 | 0.91 | S1PR1 (0.56) | S1PR1S1PR3S1PR4S1PR5GSTM2 | |
| SCHEMBL6762713 | 0.89 | GSTM2 (0.57) | S1PR1S1PR3S1PR4S1PR5GSTM2 | |
| SCHEMBL30139964 | 0.88 | S1PR4 (0.54) | S1PR1S1PR3S1PR4S1PR5SELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120301457-A1 | LIPID COFACTORS FOR FACILITATING PROPOGATION OF PRPsc | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR NIH | 2012-11-29 | — | — | US | disclosed |
| US-20120301457-A1 | LIPID COFACTORS FOR FACILITATING PROPOGATION OF PRPsc | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR NIH | 2012-11-29 | — | — | US | disclosed |
| US-20040018601-A1 | Method for generating pure populations of mobile mebrane-associated biomolecules on supported lipid bilayers | BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2004-01-29 | — | — | US | disclosed |
| US-20020009807-A1 | Lipid bilayer array method and devices | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120301457-A1 | LIPID COFACTORS FOR FACILITATING PROPOGATION OF PRPsc | PRNP, PRPH, PRPS1 | S1PR1 1179/4885S1PR3 1135/4885S1PR4 1112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.