Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397639 | 0.87 | L3MBTL1 (0.63) | L3MBTL1RAB9ANPC1IDO1MEN1 | |
| SCHEMBL29787818 | 0.84 | L3MBTL1 (0.53) | L3MBTL1RAB9ANPC1IDO1MEN1 | |
| SCHEMBL13995742 | 0.84 | L3MBTL1 (0.53) | L3MBTL1RAB9ANPC1IDO1MEN1 | |
| SCHEMBL18232477 | 0.83 | ANPEP (0.54) | L3MBTL1ALDH1A1OPRM1OPRK1CYP1A2 | |
| SCHEMBL6566603 | 0.83 | GAA (0.56) | RAB9AMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL25479303 | 0.83 | LMNA (0.57) | L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29579969 | 0.83 | L3MBTL1 (0.70) | L3MBTL1RAB9ANPC1IDO1MEN1 | |
| SCHEMBL29787785 | 0.82 | MEN1 (0.54) | L3MBTL1RAB9ANPC1IDO1MEN1 | |
| SCHEMBL12659603 | 0.81 | CHRM2 (0.53) | L3MBTL1NPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8278011 | 0.81 | L3MBTL1 (0.58) | L3MBTL1RAB9ANPC1IDO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |