Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 18/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP51A1 | Q16850 | 3/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | FYN | P06241 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1722926 | 0.87 | CYP3A4 (0.46) | CYP3A4LMNACYP51A1NR1I2FYN | |
| SCHEMBL1723212 | 0.86 | CYP3A4 (0.45) | CYP3A4LMNACYP51A1NR1I2FYN | |
| SCHEMBL1723511 | 0.86 | CYP3A4 (0.57) | CYP3A4LMNACYP51A1NR1I2FYN | |
| SCHEMBL1722991 | 0.85 | CYP3A4 (0.56) | CYP3A4LMNACYP51A1NR1I2FYN | |
| SCHEMBL1723739 | 0.84 | CYP3A4 (0.42) | CYP3A4LMNACYP51A1NR1I2FYN | |
| SCHEMBL3338694 | 0.84 | CYP3A4 (0.64) | CYP3A4LMNACYP51A1NR1I2FYN | |
| SCHEMBL3338267 | 0.84 | CYP3A4 (0.48) | CYP3A4LMNACYP51A1NR1I2FYN | |
| SCHEMBL3336892 | 0.83 | CYP3A4 (0.53) | CYP3A4LMNACYP51A1NR1I2FYN | |
| SCHEMBL8718393 | 0.78 | CYP3A4 (0.56) | CYP3A4LMNACYP51A1NR1I2FYN | |
| SCHEMBL1723655 | 0.78 | CYP3A4 (0.56) | CYP3A4LMNACYP51A1NR1I2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343980-A1 | TRIAZOLE ANTIFUNGAL AGENTS | Wu, Nian (US) | 2011-07-20 | — | — | EP | disclosed |
| US-20100143455-A1 | Triazole antifungal agents | WU NIAN | 2010-06-10 | — | — | US | disclosed |
| US-20100143455-A1 | Triazole antifungal agents | WU NIAN | 2010-06-10 | — | — | US | disclosed |
| US-20100143455-A1 | Triazole antifungal agents | WU NIAN | 2010-06-10 | — | — | US | disclosed |
| WO-2010027496-A1 | TRIAZOLE ANTIFUNGAL AGENTS | WU NIAN (US) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100143455-A1 | Triazole antifungal agents | CYP3A7, ERG28, UGT1A7 | CYP3A4 33/4885LMNA 4116/4885CYP51A1 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.