Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 3/20 | 0.47 |
| ▸ | FNTB | P49356 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740890 | 0.84 | GAA (0.55) | NPSR1FNTAFNTBALDH1A1SMN1; SMN2 | |
| SCHEMBL3955074 | 0.84 | GAA (0.55) | NPSR1FNTAFNTBALDH1A1SMN1; SMN2 | |
| SCHEMBL16013365 | 0.83 | ALDH1A1 (0.48) | NPSR1USP2ALDH1A1TP53ALOX15 | |
| Fluoride SCHEMBL28465175 | 0.83 | GAA (0.53) | NPSR1FNTAFNTBALDH1A1SMN1; SMN2 | |
| SCHEMBL30340371 | 0.81 | NPC1 (0.50) | ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL29416376 | 0.81 | NPC1 (0.50) | ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL31052770 | 0.81 | FDPS (0.44) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL14052936 | 0.80 | FDPS (0.51) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL14053150 | 0.80 | FDPS (0.51) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL31657720 | 0.79 | FNTA (0.52) | FNTAFNTBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015169723-A1 | INSECTICIDAL COMPOUNDS BASED ON THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-11-12 | — | — | WO | disclosed |