SCHEMBL17242010

SCHEMBL17242010

c1ccc(-c2ccc3c4cccc5c(-c6ccccc6)ccc(c6cccc2c63)c54)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.43
CDK4 P11802 1/20 0.42
CCND1 P24385 1/20 0.42
METAP2 P50579 1/20 0.39
TNF P01375 1/20 0.39
ALDH1A1 P00352 6/20 0.39
HPGD P15428 3/20 0.39
HSD17B10 Q99714 3/20 0.39
BACE1 P56817 1/20 0.39
CYP1A2 P05177 1/20 0.39
THRB P10828 1/20 0.39
MAP4K4 O95819 1/20 0.38
CSF1R P07333 1/20 0.38
FGFR1 P11362 1/20 0.38
PDGFRA P16234 1/20 0.38
LTK P29376 1/20 0.38
KDR P35968 1/20 0.38
MAPK8 P45983 1/20 0.38
CSNK1A1 P48729 1/20 0.38
LIMK1 P53667 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29444814 1.00 PARP1 (0.43) PARP1CDK4CCND1METAP2TNF
SCHEMBL2448362 1.00 PARP1 (0.43) PARP1CDK4CCND1METAP2TNF
SCHEMBL15672997 0.93 PARP1 (0.39) PARP1CDK4CCND1METAP2TNF
SCHEMBL634392 0.91 ALDH1A1 (0.48) PARP1CDK4CCND1METAP2TNF
SCHEMBL18660122 0.89 CDK4 (0.42) PARP1CDK4CCND1METAP2TNF
SCHEMBL29728323 0.84 ALDH1A1 (0.53) PARP1METAP2TNFALDH1A1HPGD
SCHEMBL3415539 0.84 ALDH1A1 (0.53) PARP1METAP2TNFALDH1A1HPGD
SCHEMBL15077964 0.83 TSHR (0.43) METAP2ALDH1A1CYP11B2MEN1KMT2A
SCHEMBL2033903 0.83 CRHBP (0.56) PARP1CDK4CCND1METAP2TNF
SCHEMBL31107072 0.83 CRHBP (0.56) PARP1CDK4CCND1METAP2TNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220145172-A1 POLYMERIC ORGANIC NANOPARTICLES WITH ENHANCED EMISSION Sony Group Corporation (JP) 2022-05-12 US disclosed
US-11230663-B2 Polymeric organic nanoparticles with enhanced emission SONY CORPORATION (JP) 2022-01-25 US disclosed
US-20190085237-A1 POLYMERIC ORGANIC NANOPARTICLES WITH ENHANCED EMISSION SONY CORPORATION (JP) 2019-03-21 US disclosed
EP-3140268-B1 CYANATED PERYLENE COMPOUNDS BASF SE (DE) 2018-07-18 EP disclosed
US-9919999-B2 Cyanated perylene compounds BASF SE (DE) 2018-03-20 US disclosed
WO-2017167631-A1 POLYMERIC ORGANIC NANOPARTICLES WITH ENHANCED EMISSION SONY CORPORATION (JP) 2017-10-05 WO disclosed
US-20170183295-A1 CYANATED PERYLENE COMPOUNDS BASF SE (DE) 2017-06-29 US disclosed
EP-3140268-A1 CYANATED PERYLENE COMPOUNDS BASF SE (DE) 2017-03-15 EP disclosed
WO-2015169935-A1 CYANATED PERYLENE COMPOUNDS BASF SE (DE) 2015-11-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170183295-A1 CYANATED PERYLENE COMPOUNDS C1R, C9, CBR1 PARP1 329/4885CDK4 2510/4885CCND1 333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.