Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | MAOA | P21397 | 6/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.52 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.48 |
| ▸ | RECQL | P46063 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | USP2 | O75604 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3192484 | 0.82 | CSNK2A2 (0.70) | MEN1KMT2AMAPTMAOACSNK2A2 | |
| Lithium SCHEMBL31438906 | 0.79 | CSNK2A2 (0.67) | MEN1KMT2AMAPTMAOACSNK2A2 | |
| SCHEMBL28012853 | 0.79 | CSNK2A2 (0.67) | MEN1KMT2AMAPTMAOACSNK2A2 | |
| SCHEMBL28036753 | 0.79 | CSNK2A2 (0.67) | MEN1KMT2AMAPTMAOACSNK2A2 | |
| SCHEMBL27952491 | 0.79 | CSNK2A2 (0.67) | MEN1KMT2AMAPTMAOACSNK2A2 | |
| Magnesium SCHEMBL30721501 | 0.79 | CSNK2A2 (0.67) | MEN1KMT2AMAPTMAOACSNK2A2 | |
| SCHEMBL5818577 | 0.77 | MEN1 (0.59) | MEN1KMT2AMAPTMAOACSNK2A2 | |
| SCHEMBL30002568 | 0.72 | MAPT (0.58) | MEN1KMT2AMAPTMAOACSNK2A2 | |
| SCHEMBL29556949 | 0.72 | GPR55 (0.55) | MEN1KMT2AMAPTMAOACSNK2A2 | |
| SCHEMBL197302 | 0.72 | GPR55 (0.55) | MEN1KMT2AMAPTMAOACSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3149190-A1 | IDENTIFICATION OF NOVEL ANTI-PERSISTER ACTIVITY FOR BORRELIA BURGDORFERI | The Johns Hopkins University (US) | 2017-04-05 | — | — | EP | claimed |
| US-20170058314-A1 | NOVEL METHODOLOGY FOR IDENTIFYING ANTI-PERSISTER ACTIVITY AND ANTIMICROBIAL SUSCEPTIBILITY FOR BORRELIA BURGDORFERI AND OTHER BACTERIA | ZHANG YING (US) | 2017-03-02 | — | — | US | claimed |
| WO-2015171225-A1 | IDENTIFICATION OF NOVEL ANTI-PERSISTER ACTIVITY FOR BORRELIA BURGDORFERI | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-11-12 | — | — | WO | claimed |
| EP-3321371-A1 | NOVEL METHODS FOR RAPID DRUG SUSCEPTIBILITY TESTING AND DRUG SCREENS FOR GROWING AND NON-GROWING CELLS OF PROKARYOTIC AND EUKARYOTIC ORIGIN | Zhang, Ying (US) | 2018-05-16 | — | — | EP | disclosed |
| EP-3149190-A1 | IDENTIFICATION OF NOVEL ANTI-PERSISTER ACTIVITY FOR BORRELIA BURGDORFERI | The Johns Hopkins University (US) | 2017-04-05 | — | — | EP | disclosed |
| US-20170058314-A1 | NOVEL METHODOLOGY FOR IDENTIFYING ANTI-PERSISTER ACTIVITY AND ANTIMICROBIAL SUSCEPTIBILITY FOR BORRELIA BURGDORFERI AND OTHER BACTERIA | ZHANG YING (US) | 2017-03-02 | — | — | US | disclosed |
| WO-2015171225-A1 | IDENTIFICATION OF NOVEL ANTI-PERSISTER ACTIVITY FOR BORRELIA BURGDORFERI | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-11-12 | — | — | WO | disclosed |