SCHEMBL5818577

SCHEMBL5818577

O=C1C(O)=C(O)C(=O)c2c(O)ccc(O)c21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 9/20 0.59
▸ KMT2A Q03164 9/20 0.59
▸ MAPT P10636 9/20 0.59
▸ MAOA P21397 4/20 0.59
▸ CSNK2A2 P19784 3/20 0.56
▸ CSNK2B P67870 3/20 0.56
▸ CSNK2A1 P68400 3/20 0.56
▸ CSNK2A3 Q8NEV1 3/20 0.56
▸ TXNRD1 Q16881 2/20 0.52
▸ CYP1A2 P05177 2/20 0.52
▸ AURKA O14965 1/20 0.52
▸ CYP1A1 P04798 1/20 0.52
▸ CDC25B P30305 1/20 0.52
▸ TXNRD3 Q86VQ6 1/20 0.52
▸ COPS5 Q92905 1/20 0.52
▸ AURKB Q96GD4 1/20 0.52
▸ TXNRD2 Q9NNW7 1/20 0.52
▸ ALDH1A1 P00352 8/20 0.52
▸ TDP1 Q9NUW8 8/20 0.52
▸ KDM4E B2RXH2 6/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3192484 0.87 CSNK2A2 (0.70) MEN1KMT2AMAPTMAOACSNK2A2
Magnesium SCHEMBL30721501 0.84 CSNK2A2 (0.67) MEN1KMT2AMAPTMAOACSNK2A2
SCHEMBL28012853 0.84 CSNK2A2 (0.67) MEN1KMT2AMAPTMAOACSNK2A2
SCHEMBL27952491 0.84 CSNK2A2 (0.67) MEN1KMT2AMAPTMAOACSNK2A2
Lithium SCHEMBL31438906 0.84 CSNK2A2 (0.67) MEN1KMT2AMAPTMAOACSNK2A2
SCHEMBL28036753 0.84 CSNK2A2 (0.67) MEN1KMT2AMAPTMAOACSNK2A2
SCHEMBL30004289 0.82 MEN1 (0.52) MEN1KMT2AMAPTMAOACSNK2A2
SCHEMBL5810491 0.82 MEN1 (0.52) MEN1KMT2AMAPTMAOACSNK2A2
SCHEMBL17242612 0.77 MEN1 (0.54) MEN1KMT2AMAPTMAOACSNK2A2
SCHEMBL198006 0.77 MAPT (0.58) MEN1KMT2AMAPTMAOACSNK2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0498707-B1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent OREAL (FR) 1995-08-02 — — EP claimed
EP-0498707-A1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent L'OREAL (FR) 1992-08-12 — — EP claimed
US-4888026-A HAIR DYES; OXIDATION RESISTANCE L'OREAL (FR) 1989-12-19 — — US claimed
WO-2006107827-A1 SKIN BONDING PROCESS CREIGHTON UNIVERSITY (US) 2006-10-12 — — WO disclosed
EP-0498707-B1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent OREAL (FR) 1995-08-02 — — EP disclosed
US-5275626-A Hair dyes L'OREAL (FR) 1994-01-04 — — US disclosed
CN-1023324-C Method of preventing polymer-scale formation SHINETSU CHEMICAL CO (JP) 1993-12-29 — — CN disclosed
EP-0498707-A1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent L'OREAL (FR) 1992-08-12 — — EP disclosed
US-4933399-A COATING INSIDE OF VESSEL WITH A CATIONIC DYE, DRYING, COATING WITH AN ANIONIC OR AMPHOTERIC POLYMER OR A HYDROXYL-CONTAINING COMPOUND IN A SOLVENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-06-12 — — US disclosed
US-4888026-A HAIR DYES; OXIDATION RESISTANCE L'OREAL (FR) 1989-12-19 — — US disclosed
CN-1035118-A A kind of method that forms polymer-scale that stops SHINETSU CHEMICAL CO (JP) 1989-08-30 — — CN disclosed
EP-0320227-A2 Method of preventing polymer-scale formation Shin-Etsu Chemical Co., Ltd. (JP) 1989-06-14 — — EP disclosed
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