Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | TSHR | P16473 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17243778 | 0.82 | TSHR (0.38) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL29176551 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL29176554 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL29176486 | 0.77 | TSHR (0.54) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL29176487 | 0.77 | TSHR (0.54) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL4955786 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL4955775 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL30743006 | 0.75 | HCRTR2 (0.45) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL17243774 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL17103748 | 0.74 | MEN1 (0.44) | ALDH1A1LMNAKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181229-B2 | Azole derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| US-9181229-B2 | Azole derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |