Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17243796 | 0.86 | ALDH1A1 (0.46) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL3180503 | 0.83 | SCD (0.43) | ALDH1A1TSHRMAPTEPHA2KDR | |
| SCHEMBL17243781 | 0.83 | EPHA2 (0.58) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL17103763 | 0.81 | ALDH1A1 (0.36) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL17103764 | 0.81 | ALDH1A1 (0.36) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL15417979 | 0.80 | FKBP1A (0.41) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL15417963 | 0.80 | SCD (0.42) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL17243782 | 0.79 | FKBP1A (0.41) | ALDH1A1KMT2AMEN1L3MBTL1EPHA2 | |
| SCHEMBL17243786 | 0.79 | MEN1 (0.44) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL17243791 | 0.78 | MEN1 (0.42) | KMT2AMEN1L3MBTL1HTTEPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181229-B2 | Azole derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| US-9181229-B2 | Azole derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |