Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17245218 | 0.93 | KMT2A (0.41) | KMT2AL3MBTL1BACE1NAAACTSK | |
| SCHEMBL17245229 | 0.91 | KMT2A (0.42) | KMT2AL3MBTL1BACE1NAAASCN9A | |
| SCHEMBL17245230 | 0.91 | NAAA (0.41) | KMT2AL3MBTL1BACE1NAAA | |
| SCHEMBL17245223 | 0.90 | KMT2A (0.43) | KMT2AL3MBTL1NAAA | |
| SCHEMBL17245217 | 0.90 | KMT2A (0.45) | KMT2AL3MBTL1NAAASCN9A | |
| SCHEMBL17245225 | 0.89 | KMT2A (0.41) | KMT2AL3MBTL1NAAA | |
| SCHEMBL17428276 | 0.89 | NAAA (0.38) | KMT2AL3MBTL1NAAASCN9ACTSK | |
| SCHEMBL16865293 | 0.87 | KMT2A (0.40) | KMT2AL3MBTL1BACE1NAAACTSK | |
| SCHEMBL17426990 | 0.85 | NAAA (0.37) | KMT2AL3MBTL1BACE1NAAASCN9A | |
| SCHEMBL17245242 | 0.85 | KMT2A (0.41) | KMT2AL3MBTL1NAAASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9700047-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-07-11 | — | — | US | disclosed |
| US-9700047-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-07-11 | — | — | US | disclosed |
| US-20170055528-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-03-02 | — | — | US | disclosed |
| US-20170055528-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-03-02 | — | — | US | disclosed |
| US-20150322051-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC | 2015-11-12 | — | — | US | disclosed |
| US-20150322051-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC | 2015-11-12 | — | — | US | disclosed |
| WO-2015171408-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170055528-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, CYP4F2 | KMT2A 2788/4885L3MBTL1 3646/4885BACE1 2579/4885 |
| US-20150322051-A1 | Macrocyclic picolinamides as fungicides | CYP4F12, CYP1A2, FKBP2 | KMT2A 3234/4885L3MBTL1 3973/4885BACE1 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.