SCHEMBL17246268

SCHEMBL17246268

c1ccc2c(c1)oc1c2c2ccccc2c2c3ccccc3n(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)c12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ATM Q13315 1/20 0.46
ALDH1A1 P00352 5/20 0.36
HTT P42858 1/20 0.36
PPARG P37231 4/20 0.36
RXFP1 Q9HBX9 4/20 0.36
NR2E3 Q9Y5X4 4/20 0.36
NCOR2 Q9Y618 4/20 0.36
NPSR1 Q6W5P4 2/20 0.36
POLB P06746 3/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TSHR P16473 1/20 0.35
BRCA1 P38398 1/20 0.35
PTPN1 P18031 1/20 0.34
LMNA P02545 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17246188 0.92 KDM4E (0.47) KDM4EL3MBTL1ATMALDH1A1HTT
SCHEMBL17246267 0.91 KDM4E (0.43) KDM4EL3MBTL1ATMALDH1A1HTT
SCHEMBL19986068 0.91 KDM4E (0.43) KDM4EL3MBTL1ATMALDH1A1HTT
SCHEMBL17228933 0.91 KDM4E (0.45) KDM4EL3MBTL1ATMALDH1A1HTT
SCHEMBL17427571 0.90 KDM4E (0.39) KDM4EL3MBTL1ATMALDH1A1HTT
SCHEMBL17246273 0.90 KDM4E (0.42) KDM4EL3MBTL1ATMALDH1A1PPARG
SCHEMBL17228932 0.86 ALDH1A1 (0.38) KDM4EL3MBTL1ATMALDH1A1HTT
SCHEMBL17246253 0.86 AHR (0.40) KDM4EL3MBTL1ALDH1A1HTTPPARG
SCHEMBL17246247 0.86 ALDH1A1 (0.40) KDM4EALDH1A1HTTPPARGRXFP1
SCHEMBL17071231 0.85 L3MBTL1 (0.46) KDM4EL3MBTL1ATMALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573839-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 US disclosed
US-10020459-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 US disclosed
US-10020459-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 US disclosed
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 US disclosed
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 US disclosed
US-9748510-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-29 US disclosed
US-9748510-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-29 US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 US disclosed