SCHEMBL17246555

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10014558	0.98	ATM (0.43)	ATMKDM4EL3MBTL1GPR3MAPT
	SCHEMBL24173618	0.96	ATM (0.42)	ATMKDM4EL3MBTL1GPR3MAPT
	SCHEMBL24676367	0.96	ATM (0.42)	ATMKDM4EL3MBTL1GPR3MAPT
	SCHEMBL10014559	0.94	ATM (0.40)	ATMKDM4EL3MBTL1GPR3MAPT
	SCHEMBL18777251	0.94	ATM (0.40)	ATMKDM4EL3MBTL1GPR3MAPT
	SCHEMBL10014541	0.94	ATM (0.50)	ATMKDM4EL3MBTL1GPR3MAPT
	SCHEMBL18416297	0.92	MAPT (0.38)	ATMKDM4EL3MBTL1GPR3MAPT
	SCHEMBL10014543	0.92	L3MBTL1 (0.41)	ATMKDM4EL3MBTL1GPR3MAPT
	SCHEMBL17246535	0.91	ATM (0.45)	ATMKDM4EL3MBTL1GPR3MAPT
	SCHEMBL22872094	0.90	KDM4E (0.37)	ATMKDM4EL3MBTL1GPR3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.