Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1081701 | 0.83 | KMT2A (0.35) | KMT2ACYP2D6PDE4APDE4BPDE4C | |
| SCHEMBL1078929 | 0.74 | KMT2A (0.35) | KMT2ACYP2D6PDE4APDE4BPDE4C | |
| SCHEMBL1078878 | 0.73 | KMT2A (0.44) | KMT2ACYP2D6 | |
| SCHEMBL4320737 | 0.68 | EPHX2 (0.36) | — | |
| SCHEMBL4426472 | 0.67 | KMT2A (0.48) | KMT2ACYP2D6PDE4APDE4BPDE4C | |
| SCHEMBL1724965 | 0.67 | POLB (0.33) | KMT2ACYP2D6PDE4APDE4BPDE4C | |
| SCHEMBL2657591 | 0.64 | GCGR (0.38) | KMT2A | |
| SCHEMBL517093 | 0.62 | ALOX5 (0.39) | KMT2ACYP2D6 | |
| SCHEMBL1081920 | 0.62 | ALOX5 (0.39) | KMT2ACYP2D6 | |
| SCHEMBL6763603 | 0.62 | MAOB (0.45) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406215-A1 | OXO-HETEROCYCLICALLY SUBSTITUTED ALKYL CARBOXYLIC ACIDS AND USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010102717-A1 | OXO-HETEROCYCLICALLY SUBSTITUTED ALKYL CARBOXYLIC ACIDS AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-16 | — | — | WO | disclosed |