Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.49 |
| ▸ | YES1 | P07947 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 15/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 14/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 13/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 13/20 | 0.44 |
| ▸ | KDR | P35968 | 11/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17247735 | 0.91 | MAPK1 (0.48) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17255286 | 0.89 | MAPK1 (0.52) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17247880 | 0.87 | MAPK1 (0.46) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17239939 | 0.85 | MAPK1 (0.46) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17247812 | 0.84 | MAPK1 (0.35) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17255278 | 0.83 | MAPK1 (0.54) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17247862 | 0.83 | MAPK1 (0.37) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17247876 | 0.83 | MAPK1 (0.52) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17255557 | 0.83 | MAPK1 (0.50) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL15885709 | 0.83 | AURKB (0.36) | MAPK1AURKBNTRK1YES1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |
| US-9783536-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| US-9783536-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| EP-2944637-A1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM Corporation (JP) | 2015-11-18 | — | — | EP | disclosed |
| EP-2944637-A1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM Corporation (JP) | 2015-11-18 | — | — | EP | disclosed |
| US-20150322063-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2015-11-12 | — | — | US | disclosed |
| US-20150322063-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322063-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | NPM1, NAP1L1, REN | MAPK1 149/4885AURKB 3921/4885NTRK1 3350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.